Pharmacology - Cancer Oncology drugs

Anti-Cancer Drugs Part-1 (MCQs) Pharmacology - Chemotherapeutic Drugs
Anti-Cancer Drugs Part-1 (MCQs) Pharmacology - Chemotherapeutic Drugs administrator 0 Views • 2 years ago

MCQs of Chemotherapeutic drugs (anticancer) part 1, very important questions for all pharmacists.

#pharmacology

#mcq

#anticancer

anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen.
Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology.

In this video and its affiliated parts in the Chemotherapeutic agents section, multiple-choice questions about anti-cancer drugs in terms of uses, common side effects, mechanism of action, drug interactions, contraindications, and many important questions that you may encounter in many exams

Mechanism of action:
The classification of anticancer drugs based on mechanism of action
Historically, they are categorized as: (1) alkylating agents
(2) antimetabolites
(3) natural products
(4) hormones and antagonists
(5) miscellaneous


Adverse effects:
Chemotherapeutic techniques have a range of side effects that depend on the type of medications used.
The most common medications affect mainly the fast-dividing cells of the body, such as blood cells and the cells lining the mouth, stomach, and intestines.
Chemotherapy-related toxicities can occur acutely after administration, within hours or days, or chronically, from weeks to years

Immunosuppression andmyelosuppression, Neutropenic enterocolitis, Gastrointestinal distress, Anemia, Nausea and vomiting, Hair loss, Secondary neoplasm, Infertility,Teratogenicity, Peripheral neuropathy, Cognitive impairment, Tumor lysis syndrome, Organ damage

Acute Complications of Chemotherapy (side effects, adverse effects)
Acute Complications of Chemotherapy (side effects, adverse effects) administrator 1 Views • 2 years ago

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Chemotherapy Drugs| Pharmacology, MOA of Anti-Cancer Drugs | Part 1 |Chemotherapy Antibiotics
Chemotherapy Drugs| Pharmacology, MOA of Anti-Cancer Drugs | Part 1 |Chemotherapy Antibiotics administrator 3 Views • 2 years ago

#chemotherapy #anticancerdrugs #cancertreatment
There are many different types of anti-cancer drugs, and each type targets cancer cells in a different way. Here are some examples of commonly used anti-cancer drugs:

Alkylating agents: Cyclophosphamide, Carmustine, and Busulfan.
Antimetabolites: Methotrexate, Fluorouracil, and Gemcitabine.
Topoisomerase inhibitors: Irinotecan, Topotecan, and Etoposide.
Mitotic inhibitors: Paclitaxel, Docetaxel, and Vinblastine.
Hormone therapy drugs: Tamoxifen, Letrozole, and Anastrozole.
Immunotherapy drugs: Pembrolizumab, Nivolumab, and Ipilimumab.
Targeted therapy drugs: Trastuzumab, Imatinib, and Bevacizumab.
Chemotherapy drugs work by targeting rapidly dividing cells, which are characteristic of cancer cells.

These drugs interfere with the ability of cancer cells to divide and grow, leading to cell death.

Chemotherapy drugs can target cancer cells in various stages of the cell cycle, including the resting phase (G0), DNA synthesis (S phase), mitosis (M phase), and other phases of the cell cycle.

Some chemotherapy drugs work by damaging the DNA in cancer cells, preventing them from dividing and replicating.

Other chemotherapy drugs target specific proteins or enzymes in cancer cells that are critical for their survival and growth, leading to their death or slowing their growth.
Anti-cancer drugs can be classified into different categories based on their mechanism of action, such as alkylating agents, antimetabolites, topoisomerase inhibitors, and monoclonal antibodies.

Alkylating agents work by adding an alkyl group to DNA, leading to DNA damage and preventing the cancer cells from dividing and growing.

Antimetabolites mimic the structure of essential molecules, such as nucleotides, needed for DNA synthesis and cell division, and interfere with cancer cell growth and replication.

Topoisomerase inhibitors target enzymes called topoisomerases, which are important for DNA replication and repair, and prevent cancer cells from dividing and growing.

Monoclonal antibodies are engineered proteins that recognize and target specific proteins or receptors on cancer cells, leading to their destruction or slowing their growth. Some monoclonal antibodies can also stimulate the immune system to attack cancer cells.
Anti Metabolites,

Alkylating, antimetabolites, Anti microtubule, Anti tumour antibiotic, topoisomerase, antimitotic, MOA



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Basic Principles of Cancer Treatment – Pharmacology | Lecturio Nursing
Basic Principles of Cancer Treatment – Pharmacology | Lecturio Nursing administrator 1 Views • 2 years ago

In this video “Basic Principles of Cancer Treatment” you will learn about:
► the definition of cytotoxic
► the meaning and location of high growth fraction cells
► different cancer treatment options
► the 3 types of chemotherapy administration strategies

This video is part of the Lecturio course “Pharmacology: Cancer Medications” ► WATCH the complete course on
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► THE PROF: Rhonda Lawes is a Certified Nurse Educator (CNE) and Assistant Professor at the University of Oklahoma. She worked as a nurse manager at the Saint Francis Hospital and the Broken Arrow Medical Center. She has completed her Ph.D. in Educational Psychology at Oklahoma State University.

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Cancer (Antineoplastic) Medications - Pharmacology - Immune System | @LevelUpRN
Cancer (Antineoplastic) Medications - Pharmacology - Immune System | @LevelUpRN administrator 3 Views • 2 years ago

Cathy covers common side effects associated with many or all cancer (antineoplastic) medications. The following specific cancer medications: doxorubicin, vincristine, cyclophosphamide, leuprolide, tamoxifen, and interferon alpha-2b.

Our Pharmacology video tutorial series is taught by Cathy Parkes BSN, RN, CWCN, PHN and intended to help RN and PN nursing students study for their nursing school exams, including the ATI, HESI and NCLEX.

#NCLEX #pharmacology #immunesystem #HESI #Kaplan #ATI #NursingSchool #NursingStudent⁠ #Nurse #RN #PN #Education #LVN #LPN #Cancer

0:00 What to Expect
0:29 Common Side Effects
2:16 Doxorubicin
2:34 Side Effects
2:51 Nursing Care
3:34 Vincristine
3:49 Side Effects
4:29 Cyclophosphamide
4:43 Side Effects
5:53 Nursing Care
5:24 Interferon Alpha-2b
5:47 Side Effects
6:27 Nursing Care
6:48 Quiz Time!

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புற்றுநோய் ( கீமோதெரபி ) | Cancer (Chemotherapy) | Tamil
புற்றுநோய் ( கீமோதெரபி ) | Cancer (Chemotherapy) | Tamil administrator 0 Views • 2 years ago

#cancer #chemotheraphy
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USMLE Hematology and Oncology 21 Oncology and Pharmacology
USMLE Hematology and Oncology 21 Oncology and Pharmacology administrator 0 Views • 2 years ago

Want to support the channel? Be a patron at:
https://www.patreon.com/LYMED Welcome to LY Med, where I go over everything you need to know for the USMLE STEP 1, with new videos every day.

Follow along with First Aid, or with my notes which can be found here: https://www.dropbox.com/sh/t5t....fdbhucbanuj9/AADX0mI

Shout out to the reddit user littlebrosencephalon for some of his notes and diagrams used here.

Our last video for our heme and onc block! This video is all on cancer pharmacology, discussing how they work and their side effects.

We start by drawing our cell cycle, seeing where we can manipulate it to stop cancerous cells from proliferating.

Our first drug class is the anti-metabolites, which are drugs that interfere with DNA synthesis. These include drugs such as : 6-MP, cladribine, 6-thioguanin, cytarabine, 5FU, methotrexate and hydroxyurea.

Our next class of drugs include topoisomerase inhibitors, which block the unwinding of DNA during replication. These include: topotecans, and etoposide.

Moving on to anti-cancer antibiotics. These stop bacterial and DNA synthesis and include bleomycin, actinomycin D, and doxorubicin.

Almost done! Next up is microtubule inhibitors, that blocks the formation and division of cells during M phase. These drugs include vinca alkaloids and paclitaxels.

The last drug class is alkylating agents, which bind and crosslink DNA. These drugs are non cell cycle specific and include busulfan, cyclophosphamide, nitrosoureas, and platinum agents like cisplatin.

That's it folks! All done with heme and onc!

Introduction to Pharmacology | Definition & Scope of Pharmacology | Pharmacology
Introduction to Pharmacology | Definition & Scope of Pharmacology | Pharmacology administrator 2 Views • 2 years ago

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This video is all about- Basic Introduction to Pharmacology | Definition, Historical landmarks and scope of pharmacology.

Pharmacology is one of the most important branches in pharmacy, it deals with the study of the drug, drug's effect on the body and body responsible for the drug which has been taken is called pharmacology. Pharmacology has two main branches- (1) Pharmacodynamic and (2) Pharmacokinetic.

The study of drugs or chemicals and the effects they have on living animals is called pharmacology. Pharmacology explains what drugs are, what they do to body functions and what the body does to them. Pharmacology also explains why a person may experience side effects when they take drugs and why there is such a wide spectrum of differences between drug actions in different people.

Once the drug is bound to a protein it exerts a therapeutic effect on the body, this is the pharmacodynamics of a drug. There is an enormous list of different drugs and their actions in the body.

Pharmacokinetics is the study of what happens to drugs once they enter the body. The main stages include:
(1) The absorption of the drug into the blood and across cell membranes to enter the cells;
(2) The distribution of the drug throughout the body
(3) The metabolism or breakdown of the drug; and
(4) The excretion of the drug from the body

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