Pharmacology - Cancer Oncology drugs


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The alkylating agents that have been explained in this video are :-
Cyclophosphamide, ifosfamide, mechlorethamine, chlorambucil, melphalan, Thio-TEPA, Busulfan, Nitrosoureas, Dacarbazine, Temozolamide and Procarbazine.
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Study this Methotrexate NCLEX mnemonic and other mnemonics with Pixorize.
Methotrexate is a medication that works by blocking or inhibiting folate. This blocks cell division, which can be used to kill rapidly-dividing cells. Due to this, methotrexate is often used as a chemotherapy to treat various forms of cancer. It is also used for its anti-inflammatory effects to treat autoimmune diseases like rheumatoid arthritis. Side effects of methotrexate include hepatotoxicity, bone marrow suppression, and gastrointestinal disturbances, including stomatitis. Folic acid supplements may help alleviate severe GI side effects, but remind patients to consult with their doctor beforehand. Finally, methotrexate is teratogenic and should not be taken by pregnant women.
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Stages of cancer explained using the TNM system for nurses, nursing / healthcare students, as well as an oncology NCLEX review.
Cancer Stages Quiz: https://www.registerednursern.....com/cancer-staging-a
Notes: https://www.registerednursern.....com/cancer-classific
Cancer can be graded and staged. These two terms each have different meanings and as the nurse you want to be familiar with the definition and the lingo used to communicate the grade and stage of your patient’s cancer.
The tumor grades of low to high can be given numerical values to reflect this rating, but it’s important to note that some forms of cancer have they own grading systems, like breast cancer which uses the Nottingham system.
Grade I: well differentiated, low grade
Grade II: moderately differentiated, intermediate grade…cells have some differentiation
Grade III: poorly differentiated, high grade
Grade IV: undifferentiated, high grade…cells are extremely abnormal
Tumor staging tells about the main tumor (location, size) and if the cancer has spread to other parts of the body like the lymph nodes or other organs.
One system you want to be familiar with as the nurse is the TNM staging system. This system is used to stage cancers with solid tumors like found in colon cancer and other types. TNM stands for tumor, nodal involvement, and metastasis.
The TNM system is used to calculate the stage of cancer. Here are the stages of cancer in this rating system:
Stage 0 cancer
Stage 1 cancer
Stage 2 cancer
Stage 3 cancer
Stage 4 cancer
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