Chemotherapy Drugs| Pharmacology, MOA of Anti-Cancer Drugs | Part 1 |Chemotherapy Antibiotics
#chemotherapy #anticancerdrugs #cancertreatment
There are many different types of anti-cancer drugs, and each type targets cancer cells in a different way. Here are some examples of commonly used anti-cancer drugs:
Alkylating agents: Cyclophosphamide, Carmustine, and Busulfan.
Antimetabolites: Methotrexate, Fluorouracil, and Gemcitabine.
Topoisomerase inhibitors: Irinotecan, Topotecan, and Etoposide.
Mitotic inhibitors: Paclitaxel, Docetaxel, and Vinblastine.
Hormone therapy drugs: Tamoxifen, Letrozole, and Anastrozole.
Immunotherapy drugs: Pembrolizumab, Nivolumab, and Ipilimumab.
Targeted therapy drugs: Trastuzumab, Imatinib, and Bevacizumab.
Chemotherapy drugs work by targeting rapidly dividing cells, which are characteristic of cancer cells.
These drugs interfere with the ability of cancer cells to divide and grow, leading to cell death.
Chemotherapy drugs can target cancer cells in various stages of the cell cycle, including the resting phase (G0), DNA synthesis (S phase), mitosis (M phase), and other phases of the cell cycle.
Some chemotherapy drugs work by damaging the DNA in cancer cells, preventing them from dividing and replicating.
Other chemotherapy drugs target specific proteins or enzymes in cancer cells that are critical for their survival and growth, leading to their death or slowing their growth.
Anti-cancer drugs can be classified into different categories based on their mechanism of action, such as alkylating agents, antimetabolites, topoisomerase inhibitors, and monoclonal antibodies.
Alkylating agents work by adding an alkyl group to DNA, leading to DNA damage and preventing the cancer cells from dividing and growing.
Antimetabolites mimic the structure of essential molecules, such as nucleotides, needed for DNA synthesis and cell division, and interfere with cancer cell growth and replication.
Topoisomerase inhibitors target enzymes called topoisomerases, which are important for DNA replication and repair, and prevent cancer cells from dividing and growing.
Monoclonal antibodies are engineered proteins that recognize and target specific proteins or receptors on cancer cells, leading to their destruction or slowing their growth. Some monoclonal antibodies can also stimulate the immune system to attack cancer cells.
Anti Metabolites,
Alkylating, antimetabolites, Anti microtubule, Anti tumour antibiotic, topoisomerase, antimitotic, MOA
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