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EKDINKARJA-PATHOLOGYNOTES|GASTRO INTESTINAL STROMAL TUMOUR|GIST|WHO CLASSIFICATION
GIST is a mesenchymal neoplasm with variable behaviour , characterized by differentiation towards the intestinal cells of cajal.
#GIST
#KIT
#PDGFRA
GROSS PATHOLOGY
well circumscribed.
Cut section of large tumours – foci of haemorrhage , cystic change and / or necrosis.
SDH deficient GIST – multi nodular growth pattern.
Invasion of surrounding organs like spleen and pancreas in aggressive tumors.
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