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54-year-old female with chronic headaches and homonymous hemianopsia. There is a heterogeneous T1-hyper- and hypointense mass arising from the sella turcica and extending into the suprasellar compartment. Focal regions of central hemorrhage with more peripheral hemosiderin staining are identified. Nodular components of the lesion demonstrate diffusion restriction. The lesion abuts, elevates, and distorts the undersurface of the optic chiasm and prechiasmatic segments of the optic nerves superiorly. There is heterogeneous postcontrast enhancement. The findings are most compatible with a craniopharyngioma. Craniopharyngioma represent benign, partially cystic sellar/suprasellar lesions. 90% are cystic, have calcifications, and/or enhance. The adamantinomatous subtype are more common in children, with the papillary type more common in adults. NMR181
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#MountSinaiLive: In honor of Brain Tumor Day, Peter Morgenstern, MD joins us to talk about what you need to know about brain tumors in children.
Dr. Peter Morgenstern is a board-certified neurosurgeon who specializes in pediatric neurosurgery. He has extensive training in the comprehensive care of children with brain tumors, hydrocephalus, spinal and cranial malformations including craniosynostosis and spina bifida, Chiari malformation, and other common pediatric neurosurgical conditions. He is particularly interested in applying minimally invasive techniques, such as neuroendoscopy, to pediatric neurosurgery. Throughout his career, Dr. Morgenstern has been praised for his thoughtful and level-headed approach to complex problems, and has been recognized for the excellence and compassion with which he cares for his patients. He is dedicated to guiding patients and their families through the difficult journey from diagnosis through treatment and follow-up.
Dr. Morgenstern has published numerous peer-reviewed articles and has won several grants and awards for his research, including the Kenneth Schulman Award from the AANS/CNS Joint Section on Pediatric Neurosurgery, and the Christopher Gaposchkin ’99 Research Prize from the Department of Neurological Surgery at Weill Cornell. His previous research has been funded by the Neurosurgery Research and Education Foundation and the Voices Against Brain Cancer Foundation. His current research focuses on pediatric brain tumors, clinical outcomes in pediatric neurosurgery and neuroendoscopy.
In his spare time Dr. Morgenstern enjoys spending time with his family, cycling, running, cooking, and playing music.
Request an appointment with Dr. Morgenstern: https://mshs.co/3My251o


16-year-old male with bitemporal hemianopsia and chronic headaches. There is circumscribed T1-hypointense, T2-hyperintense mass centered within the sellar/suprasellar region. The lesion demonstrates T2/FLAIR-hyperintense signal, facilitated diffusion, and a thin peripheral rim of postcontrast enhancement. There are lobular cystic components which extend into the enlarged sella turcica. This is a case of an adamantinomatous craniopharyngioma. Craniopharyngiomas occur with a bimodal distribution. The first peak occurs between 10 and 14 years of age while the second occurs in middle-aged adutls. Pediatric cases are mostly composed of the adamantinomatous subtype while the papillary subtype comprises the majority of cases in middle-aged adults. Cases occur in males and females about equally. Differential includes Rathke cleft cyst, cystic pituitary adenoma, epidermoid and intracranial teratoma.
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Endoscopic Endonasal Craniopharyngioma surgery is performed for the majority of these tumors. This is most ideal when the tumors are behind the optic chiasm (nerves from the eyes). In this video, Dr. Daniel Kelly, director of the Pacific Pituitary Disorders Center at Providence Saint John's Health Center demonstrates the endoscopic surgical removal of a craniopharyngioma while preserving the normal gland and blood vessels. This allows for a better chance of vision preservation as well as pituitary gland function. This patient did well with good pituitary gland function and vision after surgery.
https://www.pacificneuroscienc....einstitute.org/pitui
310-582-7450


12-year-old male with chronic headaches and new onset diabetes insipidus. There is a circumscribed centrally cystic lesion arising from the anterior surface of the infindibulum. The central cystic component demonstrates signal intensity slightly greater than the surrounding CSF space on the T1-weighted image. There is FLAIR hemorrhage/proteinaceous fluid centrally. The high-resolution fluid sensitive sequences demonstrate a lesion with a thin margin abutting the posterior and inferior aspect of the optic chiasm with slight displacement and deformity. The lesion demonstrates a thin enhancing margin. The general differential includes adamantinomatous craniopharyngioma, Rathke’s cleft cyst, and infindibular cyst. This is an adamantinomatous craniopharyngioma. Craniopharyngioma are though to arise via two mechanisms: as remnants of the craniopharyngeal duct, while the second is from squamous epithelial cells in the pars tuberalis of the adenohypophysis. 75% of the adamantinomatous subtype tend to be in the suprasellar compartment. NMR182
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