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This was presented at Neuroendocon 2021.
Though complete resection of craniopharyngioma is desirable
for lower recurrence rates, it is hindered by functional
preservation. Currently, a trend toward less radical surgical
approaches is observed. In a multicenter study of children and adolescents with craniopharyngioma, KRANIOPHARYNGEOM
2007, it was observed that the realized treatment was more
radical (p = 0.01) in patients recruited between 2001 and 2007
(38%) when compared with patients treated between 2007 and
2012 (18%).
Cystic craniopharyngiomas
present a unique challenge because of the possibility
of recurrence of cyst irrespective of the modality of initial
treatment. Almost 90% of craniopharyngiomas have a cystic
component.3 The presence of a cyst in craniopharyngioma
can account for major total bulk of the tumor, and a predominantly
cystic tumor is seen in 60% of craniopharyngiomas. The treatment of cystic craniopharyngioma in children is varied. The treatment ranges from radical excision to direct radiotherapy. As the morbidity of excision is high, more conservative approaches are used.
The traditional approach to cystic craniopharyngioma is a
variable extent of microsurgical resection. Ommaya reservoir
is often placed in the residual cyst for repeated aspiration or
intracavitary therapy. However, the malposition of reservoir
is not uncommon. In such circumstances, a neuroendoscopic
approach provides a less invasive and more accurate technique
to deal with cystic craniopharyngiomas. Since 2013, we follow
the endoscopic transventricular approach for intra- and
paraventricular cystic craniopharyngiomas.
Transventricular endoscopy is a minimally invasive treatment for cystic craniopharyngiomas. Endoscopic transventricular approach is a safe alternative for initial treatment of suprasellar cystic craniopharyngioma in children.
Konar S. Kulkarni AV, Shukla D, Mishra T, Devi BI, Peer S, Lanka V. Management options for suprasellar cystic craniopharyngioma: Endoscopic Transventricular Approach and Microsurgical Approach. J Neurosci Rural Pract 2021;12:121–127. DOI https://doi.org/10.1055/s-0041-1722839


Dr. Garni Barkhoudarian discusses the background and treatment of craniopharyngiomas at the 2015 California Pituitary Conference. These include surgical resection, radiation therapy, cyst drainage options and immunotherapy.
https://pacificneuro.org
https://pacificneuro.org/barkhoudarian
https://pacificpituitary.org | https://pacificbraintumor.org | 310-582-7450


Watch Dr. Jeffrey Wisoff, MD. doing his lecture ‘The Role of Resection in Craniopharyngioma’ at the 2020 International Web-Based Neurosurgery Congress (2020 IWBNC) - May 21-23, 2020.
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For Inspiration Friday and Brain Tumor Awareness Month, we celebrate the survivors of craniopharyngioma. Many years ago, the father of modern neurosurgery, Harvey Cushing, called this tumor "the most formidable of intracranial tumors."
While very survivable, these tumors occupy the middle of the bran and can encroach upon many vital parts responsible for body function, temperature regulation, memory, vision, metabolism, behavior, stress response...the list goes on. These tumors occur in children and adults and they are highly recurrent.
A parent of a 19-year survivor recently remarked that she could not believe that in 20 years, there still is no improvements in treatments of these tumors to ensure better outcomes.
The new mission of the Raymond A. Wood Foundation is about focusing in on tumors like these that occupy this region of the brain because it's time to find a better way.
These are the faces of survivors from around the world - sons, daughters, sisters, brothers, moms, dads, friends - that embody the true meaning of strength and resilience. When COVID is in our rearview, these faces will still be up against the daily challenges that come with these tumors.
Please consider supporting RAWF's new mission. Its time for a better way https://www.rawoodfoundation.org/donate


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