Lymph node pathology - Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL)

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07/15/23

In this discussion we focus on the different histological presentations of NLPHL with stress on their histological mimics. Relevant IHC stains are explained in exhaustive detail, highlighted through virtual cases. The lecture is aligned to the latest WHO Blue Book on Haematolymphoid Tumours (5th ed.). The issues discussed are
1) The conundrum of pattern A/B NLPHL versus nodular patterned lymphocyte rich classic Hodgkin lymphoma and PTGC
2) The dilemma of pattern E (THRLBCL-like) NLPHL versus T cell histiocyte rich large B cell lymphoma
Virtual slides courtesy of
1) https://www.virtualpathology.l....eeds.ac.uk/slides/li
2) https://www.pathology.med.umich.edu/apps/slides/