Linking Lynch Syndrome and microsatellite instability in tumours

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06/29/23

Dr Stadler speaks with ecancer at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting about links between tumours with high micro satellite instability (MSI-H) and the hereditary condition Lynch syndrome.

She describes how inherited mutations in Lynch syndrome-associated genes were found in 16% of people with MSI-H tumors, compared to 1.9% of those with MSI-I tumors and only 0.3% of those with MSS tumors.

Dr Stadler encourages screening and genetic counselling for all those eligible.

For more on these results, watch her presentation of the findings at a press session here, and read our news coverage here.