Linking Lynch Syndrome and microsatellite instability in tumours

Dr Stadler speaks with ecancer at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting about links between tumours with high micro satellite instability (MSI-H) and the hereditary condition Lynch syndrome.

She describes how inherited mutations in Lynch syndrome-associated genes were found in 16% of people with MSI-H tumors, compared to 1.9% of those with MSI-I tumors and only 0.3% of those with MSS tumors.

Dr Stadler encourages screening and genetic counselling for all those eligible.

For more on these results, watch her presentation of the findings at a press session here, and read our news coverage here.