Chronic myeloid leukaemia Pathology lecture in hindi||Leukaemia||chronic myeloid leukaemia in hindi
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Chronic myeloid leukemia (CML) is also known as chronicmyelogenous leukemia. It's a type of cancer that starts in certain blood-forming cells of the bone marrow.
In CML, a genetic change takes place in an early (immature) version of myeloid cells -- the cells that make red blood cells, platelets, and most types of white blood cells (except lymphocytes). This change forms an abnormal gene called BCR-ABL, which turns the cell into a CML cell. The leukemia cells grow and divide, building up in the bone marrow and spilling over into the blood. In time, the cells can also settle in other parts of the body, including the spleen. CML is a fairly slow growing leukemia, but it can change into a fast-growing acute leukemia that's hard to treat.
CML occurs mostly in adults, but very rarely it occurs in children, too. In general, their treatment is the same as for adults.
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