In the human body, liver performs a lot of useful functions that allows your body to expunge the bad elements. This organ changes the nutrients and other chemicals that you consume into something productive for the body. But besides from the good food nutrients, some of the things that enter this organ have extremely harmful properties, like cancer-causing agents.

What is Liver Cancer?
In medical terms, it is called Hepatocellular Carcinoma.
Liver cancer is cancer that begins in the cells of your liver. Your liver is a football-sized organ that sits in the upper right portion of your abdomen, beneath your diaphragm and above your stomach.
Several types of cancer can form in the liver. The most common type of liver cancer is hepatocellular carcinoma, which begins in the main type of liver cell (hepatocyte). Other types of liver cancer, such as intrahepatic cholangiocarcinoma and hepatoblastoma, are much less common.

Cancer that spreads to the liver is more common than cancer that begins in the liver cells.
There are 2 types of liver cancer:
1. Primary liver cancer is cancer that forms in the tissues of the liver. It is extremely difficult to identify it at an early stage.

2. Secondary liver cancer begins in another part of the body and then spreads to the liver. Commonly secondary cancer, and it most often spreads from colon, lung, and breast cancers. When this happens, the disease is not liver cancer. It is named for the organ where it began, and cancer in the liver is secondary.

Risk Factors of Liver Cancer:

1. Viral Hepatitis -
• Viral hepatitis is one of the largest risk factors for this type of cancer.
• Hepatitis B and Hepatitis C face an increased risk of developing adult primary liver cancer.

2. Cirrhosis -
a. Cirrhosis is a disease in which liver cells become damaged and are replaced by scar tissue. People with cirrhosis have an increased risk of liver cancer.
b. There are several possible causes of cirrhosis, like abuse of alcohol or have chronic hepatitis B or C infections.

3. Age and Gender
a. Liver cancer is much more common in males than in females.

4. Inherited Metabolic Diseases
a. Certain inherited metabolic diseases can lead to cirrhosis. People with hemochromatosis absorb too much iron from their food. They are more likely to develop cirrhosis because of the high levels of iron in their liver.
b. Other rare diseases that increase the risk of liver cancer include tyrosinemia, alpha1-antitrypsin deficiency, porphyria cutanea tarda, glycogen storage diseases, and Wilson disease.

5. Diabetes and Obesity -
a. Diabetes can also increase the risk of liver cancer, usually in patients who have other risk factors such as heavy alcohol consumption and/or chronic viral hepatitis.
b. Obesity may increase the risk of developing liver cancer, probably because it can result in fatty liver disease and cirrhosis.

6. Anabolic Steroids -
a. Anabolic steroids are male hormones used by some athletes to increase their strength. Long-term anabolic steroid use can slightly increase the risk of hepatocellular cancer.

7. Arsenic -
a. Chronic exposure to drinking water contaminated with naturally occurring arsenic, such as that from some wells, increases the risk of some types of liver cancer.

Symptoms of Liver Cancer:
1. A hard lump or swelling found on the right side of the abdomen, just below the ribs
2. Pain or discomfort on the upper side of the abdomen or by the right side of the shoulder blade
3. Jaundice, or the yellowing of the skin or the whites of the eyes or dark-coloured urine
4. Nausea, loss of appetite or feeling full shortly after you begin to eat
5. Unexplained weight loss
6. Fatigue
7. Swollen abdomen, bleeding (the symptoms of cirrhosis)

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The American Liver Foundation presents "Don's Liver Cancer Story" as part of the 2021 Liver Cancer Conference as told by Don Melillo himself.

More information about liver cancer can be found online at the American Liver Foundation website at https://liverfoundation.org/fo....r-patients/about-the

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We believe it’s important for our patients to receive a bespoke treatment plan. What options are available for liver cancer? Consultant HPB and Liver Transplant Surgeon Professor Brian Davidson uncovers the latest approaches.

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Richard Finn, MD, provides insight on the curative treatments available to patients with liver cancer and cirrhosis, including liver transplant and chemoembolization.

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NYU Langone Associate Professor of Medicine, Jennifer Wu speaks on Liver Cancer

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Learn more about NYU Langone’s Perlmutter Cancer Center: http://nyulangone.org/location....s/perlmutter-cancer-

AstraZeneca’s cancer immunotherapy Imjudo (tremelimumab) has won its first ever FDA approval after several trial setbacks in other cancers. The anti-CTLA-4 monoclonal antibody was approved in combination with the company’s PD-L1 inhibitor Imfinzi for the treatment of unresectable hepatocellular carcinoma, the most common type of liver cancer. The drug combination is also the first dual immunotherapy treatment regimen in liver cancer to receive FDA approval.

Visit Xtalks for more details on this story,
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Learning about liver cancer can be intimidating. Let our experts walk you through the facts, the questions, and the answers to help you better understand this condition.     For more reading visit: https://mayocl.in/3q8Lzwk
When it comes to your health, Mayo Clinic believes credible and clear information is paramount. There’s a lot to learn about liver cancer. We’re here to help.            

0:00 Introduction 
0:22 What is liver cancer? 
2:04 Who gets liver cancer? / Risk factors
3:02 Symptoms of liver cancer
3:52 How is liver cancer diagnosed?  
4:48 Treatment options      
5:36 Coping methods/ What now?     
6:00 Ending   

Still have questions? That’s okay.  - https://bit.ly/36nsmA0       

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· Mayo Clinic Minute: When colon cancer spreads to the liver   - https://bit.ly/34Rv68E

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