Sarcomas, Soft Tissue


Soft Tissue Sarcoma (STS) is the type of cancer which developed in soft tissue (mesenchymal tissue) of the body, which includes, muscle, blood vessels, Fat tissue, connective tissue. STS categorized, depending upon tissue origin. There are more than 50 subcategory of STS. Histological diagnosis is very important, to plan management. Biopsy needs to be done, before definitive treatment. After histopathology examination, Special dye test needs to be done to get exact diagnosis of STS, known as immuno histo chemical test (IHC). Some common types of STS are:
1. Liposarcoma
2. Synovial Sarcoma
3. Undifferentiated Pleomorphic Sarcoma (UPS)
4. Angiosarcoma
5. Rhabdomyosarcoma
STS usually metastasize to lung and rarely other part of body also like lymph nodes, liver, bone etc. Metastatic work-up depends upon histology, location, & grade. Usually we need to get CT chest, USG or PET-CT whole body.
Treatment Options
1. Surgery - Surgical Removal is the most important part of the treatment. Complete removal of tumor and preserving maximal function, is the treatment of choice now a days.
2. Radiation Therapy - it needs to be given to prevent local recurrence of tumor. Different methods of radiation therapy are present, which includes: Brachytherapy, External Beam Radio therapy (EBRT), intraoperative RT.
3. Chemotherapy - Usually STS are chemoresistant disease, so we need to found out in which cases it should be given. Criteria of chemotherapy includes multiple factors, like location, size, grade, margins. Sarcoma specialized sarcoma tumor board decides the introduction of chemotherapy in particular cases.
For more information contact
Dr. Lokesh Garg
for free WhatsApp consultation - +91 8882276327
Mail ID - waytoheal.mskonco@gmail.com
Website - www.waytoheal.co.in


A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Synovial sarcomas are malignant soft tissue tumors that most often arise in the extremities of young adults. Despite the name, they are NOT related to synovium nor do they arise from synovial cells. This video discusses the pathologic features of monophasic and biphasic synovial sarcoma including immunostains, molecular testing, the major differential diagnoses, and potential diagnostic pitfalls. Many thanks to Dr. Maryna Slisarenko from Ukraine for typing up the English & Ukranian transcripts so that this video has better closed captions/subtitles! You can download the English transcript here: https://www.dropbox.com/s/iz5j....j74o7rec7qr/synovial
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
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Soft Tissue Sarcoma By Dr. Vivek Verma
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This is an excerpt from my Basic Soft Tissue Pathology Cases video (full video here: https://kikoxp.com/posts/3784).
More on Alveolar soft part sarcoma (ASPS)
Video (ASPS vs Alveolar Rhabdomyosarcoma): https://kikoxp.com/posts/4580
WSI digital slides: https://kikoxp.com/posts/8197
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
You might like my Twitter/social media 101 guide: https://kikoxp.com/posts/15217
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jer....ad_gardner1/content?
Facebook: https://www.facebook.com/JMGardnerMD/