Salivary Gland Cancer

Salivary Gland Neoplasms
Salivary Gland Neoplasms administrator 3 Views • 2 years ago

This is a short video on the most common neoplasms (tumors and cancers) of the salivary glands.

I created this presentation with Google Slides.
Image were created or taken from Wikimedia Commons
I created this video with the YouTube Video Editor.

ADDITIONAL TAGS:
Neoplasms of the salivary glands
Pleomorphic adenoma
Warthin's tumor
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
By Ed Uthman, MD -
http://web2.airmail.net/uthman/specim..., Public Domain, https://commons.wikimedia.org/w/index...

Pleomorphic adenoma
Most common benign salivary gland tumor
Usually in parotid gland
Pleomorphic: variable appearance architecturally
Parenchymatous glands with myoepithelium
Stroma with epithelial tissue
Diagnose with fine needle aspiration (best: 90% sensitivity), US, CT, or MRI
Treat with surgical resection (parotidectomy), but it's a recurrent issue; can become carcinoma
Pleomorphic adenoma
Warthin's tumor
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
BOTTOM: By Schomynv - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index...
LEFT:
CC BY-SA 3.0, https://commons.wikimedia.org/w/index...

Warthin’s tumor
AKA papillary cystadenoma lymphomatosum
Second most common benign salivary gland tumor
Usually in parotid
Histo: germinal centers, cystic spaces, many lymphocytes, condensed chromatin (pyknotic) nuclei
Associated with smoking, older people
Tumor is slow growing, often painless
Pleomorphic adenoma
Warthin's tumor
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
CC BY-SA 3.0, https://commons.wikimedia.org/w/index...

Mucoepidermoid carcinoma
Most common malignant salivary gland tumor
Usually starts in parotid, can also be found outside of salivary gland
Histo: contains mucinous cells and squamous cells
Tumor is slow growing, often painless
Associated with CMV
Pleomorphic adenoma
Warthin's tumor
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
By No machine-readable author provided. KGH assumed (based on copyright claims). - No machine-readable source provided. Own work assumed (based on copyright claims)., CC BY-SA 3.0, https://commons.wikimedia.org/w/index...
By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index...

Adenoid cystic
carcinoma
Second most common malignant salivary gland tumor
Common tumor of the submandibular gland
Can also involve other tissues
Slow growing
Can have distant metastases: eye, lung, brain, sinuses, trachea, breast
Treatment is surgical resection, radiation
Pleomorphic adenoma
Warthin's tumor
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
TOP:
By Jto410 - In my clinical work as a diagnostic radiologist, CC BY-SA 3.0, https://commons.wikimedia.org/w/index...

BOTTOM:
By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index...

Salivary Gland Tumors,  Salivary gland cancers and benign tumors
Salivary Gland Tumors, Salivary gland cancers and benign tumors administrator 0 Views • 2 years ago

Salivary gland Neoplasm can be Benign or Malignant.
Majority of cases are c.
Malignant cancers are rare.
Malignant salivary gland tumors usually present after the 6th decade of life, whereas benign lesions present in the 4-5th decade of life.
The salivary glands make saliva and release it into the mouth.
There are 3 pairs of major salivary glands:
Parotid glands: These are the largest salivary glands and are found in front of and just below each ear. Most major salivary gland tumors begin in this gland.
Sublingual glands: These glands are found under the tongue in the floor of the mouth.
Submandibular glands: These glands are found below the jawbone.
here are also hundreds of small (minor) salivary glands lining parts of the mouth, nose, and larynx that can be seen only with a microscope. Most small salivary gland tumors begin in the palate (roof of the mouth).
Signs and Symptoms.
Some cases Salivary gland cancer can be asymptomatic.
In other cases:
A lump (usually painless) in the area of the ear, cheek, jaw, lip, or inside the mouth.
Fluid draining from the ear.
Trouble swallowing or opening the mouth widely.
Numbness or weakness in the face.
Pain in the face that does not go away.
Causes:
No single cause is known for Salivary gland Cancer, but Radiation exposure, head and neck radiation therapy, has been linked to parotid gland carcinomas, 15 years after the event.
Cigarette smoking and alcohol directly, are not associated with salivary gland tumor.
Salivary tumor among kids are very rare.
Most of cases occurs sixth decade of life.
Overall 5-year survival rate of salivary cancer is 70 % but highly dependent on stage and type of cancer.
Diagnosis.
Most common diagnostic tests are: Common tests are: MRI (magnetic resonance imaging): and CT scan (CAT scan). Endoscopy and Phisical examination.

Most patients with early-stage lesions that are resectable generally tend to undergo surgery as their initial therapeutic approach, whereas those with advanced or unresectable cancers tend to be treated with radiotherapy alone or chemoradiotherapy.
By BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. - Own work, CC BY 3.0,
https://commons.wikimedia.org/....w/index.php?curid=29
By Jto410 - In my clinical work as a radiologist, CC BY-SA 3.0, https://commons.wikimedia.org/....w/index.php?curid=28

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