Neuroendocrine Tumor of the Pancreas


Pancreatic NET or Pancreatic Neuroendocrine Tumours are a rare form of cancer with symptoms that are often perceived to simply be stomach problems related to diet or stress.
This film presents the story of Xavier, who was diagnosed with Pancreatic NET around 5 years ago. In the beginning Xavier attributed his stomach pains, headaches and high blood pressure to lifestyle, diet and exercise.
However after visiting a gastrointestinal specialist, it was identified that Xavier had pancreatic NET. Pancreatic NET is a chronic, not acute disease meaning that it can have a devastating effect upon lifestyle.
Having undergone extensive surgeries Xavier's life changed tremendously and he now leads a nearly normal life, going back to work and spending time with his friends and family.
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Le cancer du pancréas demeure l'un des cancers les plus redoutés. Chaque année en France, 14.000 nouveaux cas sont constatés, majoritairement des patients de plus de 50 ans. Il s'agit d’un cancer en constante augmentation et souvent diagnostiqué tardivement, compromettant les chances de guérison.
Quels sont les signes avant-coureurs ? Pourquoi ce cancer est-il si difficile à traiter ? Ou en est la recherche ? Le Dr Cindy Neuzillet, gastro-entérologue oncologue, et Joëlle, en rémission d'un cancer du pancréas, répondent aux questions sur cette maladie.
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Pancreatic cancer is caused by the abnormal growth of cells in the pancreas.
The pancreas is located deep inside the abdomen behind the stomach in an area called the retroperitoneum and is surrounded by the liver, spleen, small intestine, and other organs.
There are two types of glands in the pancreas: exocrine glands and endocrine glands. Exocrine glands produce pancreatic enzymes that help to digest proteins and starches. These enzymes are secreted into the pancreatic duct and empty into the first part of the small intestine, called the duodenum, when eating.
Endocrine glands (found in clusters called islets) produce insulin and other regulatory hormones. These hormones circulate through the body via the bloodstream and keep various systems in check. For example, insulin helps regulate blood sugar levels.
Pancreatic tumors can be benign (noncancerous) or malignant (cancerous). Benign tumors are generally not life-threatening and can often be removed. Malignant tumors, on the other hand, can be life-threatening, as they sometimes invade surrounding tissues and organs and can spread to distant sites in the body.
Pancreatic cancers are divided by location. Proximal pancreatic cancers are cancers that develop in the uncinate process and head of the pancreas. Distal pancreatic cancers are cancers that develop in the body and tail of the pancreas.
Pancreatic cancers can develop in both exocrine and endocrine cells. Exocrine tumors are more common than endocrine tumors (also referred to as islet cell tumors or neuroendocrine tumors).
The pancreas is an abdominal gland consisting of two major parts, thus corresponding to the two types of pancreatic cancer. The endocrine part of the pancreas produces hormones, with insulin being the most notable.
Tumors within this region of the pancreas are sometimes referred to as pancreatic neuroendocrine tumors (PNETS), and may or may not cause excessive amounts of hormones such as insulin. The exocrine component is regarded for making enzymes, useful for metabolism and digestion of food. Exocrine tumors are by far the most common form of pancreatic cancer and can include quite a few specific subtypes.
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