For Childhood Cancer Awareness Month, PhD student Antonio Romo-Morales talks about his research on a rare children's cancer called Ewing sarcoma. Antonio works in the ICR's Sarcoma Molecular Pathology Team, led by Professor Janet Shipley, and his research is gratefully supported by the Elin Rose Appeal.

This is how I found out I had cancer, it was hard and awful but I'm grateful for amazing family and friends who supported me the whole way.

UPDATE 25/05;
I am now cancer free, and have been for nearly a year :D
As much as cancer is a part of my life, I'd like to move on and not have it loom over me, therefore I've removed the comments on this video, if I want a reminder I know where to look. But for now I'd like to focus on my future and not on the past.

Happy endings do exist and to anyone else going through something similar, know that you are not alone and we can get through this, sending you best wishes!

Ewing sarcoma is a diaphysial bone tumor which comes under the differential of "Small round cell tumors". The tumor is aggressive , occurs in children less than 20 years and often presents as knee pain with bone mass.
X ray shows lamellate periosteal reaction called as Onion skin appearance in around 50% of cases. On microscopy there are sheets of small round cells and the cytoplasm is clear due to presence of glycogen.
Confirmation is done by IHC CD99, FLI1. Genetic translocation is between chromosome t(11:22) in 95% of cases. Also you could use PAS stain for confirmation of glycogen.

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Chad was first diagnosed with Ewing’s Sarcoma at the age of 23 after he experienced pain in his lower back. Ten years later at the age of 33, Chad experienced a recurrence and was diagnosed for a second time with cancer. This is his story.

Treatment of Ewing’s sarcoma using localized delivery of thermo-sensitive liposomal doxorubicin and MR-HIFU mild hyperthermia

Ewing's sarcoma is a primary bone cancer that affects mainly children and adolescents. It's one of a group of cancers known collectively as the Ewing sarcoma family of tumors -- ESFT or sometimes just EFT. It's the second most common bone cancer in children, but it's also relatively uncommon. It accounts for only 1% of all childhood cancers. Although it can occur at any age, it very rarely occurs in adults over the age of 30.

Because many illnesses can cause the same symptoms as Ewing's sarcoma, it's sometimes missed in its early stages. But early diagnosis and treatment is important. If found early enough, before it spreads to multiple organs, Ewing's sarcoma can be treated successfully in 50% to 75% of cases.

What Makes Ewing's Sarcoma a Primary Bone Cancer?
Primary bone cancer is cancer that originates in bone cells. The other way cancer can occur in bones is after spreading there from another part of the body through a process called metastasis. When it does, it's called secondary bone cancer. Secondary bone cancer is the same type of cancer that exists in the tissue or organ where it first occurred. For instance, breast cancer that spreads to the bones is still made up of breast cancer cells.

Researchers think that Ewing's sarcoma begins in a certain kind of primitive cell. And although the tumors typically start forming in bone, they can also start in the same kind of cells outside of bone. When this occurs, it's called an extraosseous Ewing's sarcoma.

Ewing tumors that grow in bone are typically found in the long bones of the legs and arms, or bones in the chest, trunk, pelvis, back, or head. In addition to the classic Ewing tumor, which is named for the doctor who first described it, James Ewing, there are two other types of bone tumor that belong to the Ewing family of tumors. One is called primitive neuroectodermal tumor or PNET. This tumor often times arises in the brain. The other is known as an Askin tumor, which usually arises in the chest wall.

There are differences in these types of tumors. But the cells that make them up are similar, they have the same DNA abnormalities, and they share proteins that aren't found in cells of other cancers. All of the cancers progress in the same way, and all are treated the same way.