SPEED Daily Shorts -102. Adenoid Cystic Carcinoma, by Dr.K.Vinayak Senthil.,
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Dr Rob Metcalf presents the Cancer Immunology Branch Case Study on Adenoid Cystic Carcinoma.

Dr Metcalf and a team of expert immunologists at the Lydia Becker Institute are analysing the tumour and immune components within blood and tumour samples using flow cytometry, mass cytometry, proteomics and immunohistochemistry/immunofluorescence to understand the biology of anti-tumour immunity and develop newer and better cancer therapies

Find out more: https://sites.manchester.ac.uk..../lydia-becker-instit

58-year-old female with chronic nasal obstruction and headaches. Centered in the left sphenoid sinus region, with invasion into the basisphenoid on the left and extension into the left petrous apex region, there is a T1-hypointense, T2/FLAIR-hyperintense, solid and cystic enhancing mass which does not restrict diffusion. The mass extends to the distal petrous canal where there is greater than 180 degrees encasement of the left internal carotid artery without narrowing of its flow void. The lesion invades and enlarges the left cavernous sinus with elevation of the overlying dural surface. The differential diagnosis includes nasopharyngeal carcinoma, carcinoma of the minor salivary glands, such as adenoid cystic, lymphoma and chondrosarcoma. The final diagnosis was high-grade adenoid cystic carcinoma of the left sphenoid sinus. Adenoid cystic carcinoma can be considered low grade which tends to be well-defined, versus high grade which is more infiltrative. It can involve the submandibular/sublingual salivary glands, lacrimal glands, nasopharynx and hard palate. NMR250

For more, visit our website at http://ctisus.com

This video is an excerpt from my one-day dermpath course in Paris, France, on October 8, 2021, for the Academie Internationale de Pathologie – Division Française (IAP French division).
Full 5 hour video of the entire course is available for free here: https://kikoxp.com/posts/8361.
WSI digital slide: https://kikoxp.com/posts/6679
Video discussing adenoid BCC vs adenoid cystic carcinoma here (at 41:31): https://kikoxp.com/posts/6682

Here's a case report we published about primary cutaneous adenoid cystic carcinoma (not the same case as this slide): https://pubmed.ncbi.nlm.nih.gov/25062259/

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB ‬

This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.

Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.

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Adenoid cystic carcinoma is a slow growing, aggressive salivary gland neoplasm. It is reported to be the second most common malignant salivary gland tumor after Mucoepidermoid carcinoma.
📄Notes for the video: https://www.hackdentistry.com/....bundles/oral-patholo

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Study resources on our website-
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📖Oral Histology Revision Ninja (Notes, Videos & MCQs): https://www.hackdentistry.com/bundles/revision-ninja-oral-histology
📖Periodontics Revision Ninja (Notes & MCQs): https://www.hackdentistry.com/bundles/perio-rn
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References and further reading:
💡Fletcher CDM. Diagnostic histopathology of tumors . 3 rd ed. Churchill Livingstone Elsevier; 2007.
💡Neville BW, Damm DD, Allen CM, Chi A. Oral and Maxillofacial Pathology. South Asian ed. Elsevier; 2016.
💡Rajendran R, Sivapathasundaram B. Shafer’s Textbook of Oral Pathology. 7th ed. Elsevier; 2012.
💡Regezzi JA, Sciubba JJ, Jordan RCK. Oral Pathology: Clinical Pathologic Correlations. 5 th ed. Elsevier; 2007.
💡Sapp JP, Eversole LR, Wysocki GP. Contemporary Oral and Maxillofacial Pathology. 2 nd ed. Mosby; 2004.
💡Bradley PJ. Adenoid cystic carcinoma of the head and neck: a review. Curr Opin Otolaryngol Head Neck Surg 2004;12(2):127-32.
💡Pinakapani R, Chaitanya NCSK, Lavanya R, Yarram S, Boringi M, Waghray S. Adenoid
💡Cystic Carcinoma of the Head and Neck– literature review. Quality in Primary Care
2015;23(5):309-14.

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In February 2016, James Parkin was diagnosed with a rare cancer of the salivary gland; a cancer type which only effects around 1 in 100,000 people in the UK each year. To support Cancer Research UK’s Right Now campaign, James is sharing his story in a moving video that shows though cancer has changed him physically, he is still the same person inside.

https://www.cruk.org/rightnow
https://jamesparkinmusic.com

Most salivary gland cancers start in the parotid glands. Around 8 in 10 (around 80%) salivary gland cancers start here. Just over 1 in 10 (just over 10%) start in the submandibular glands. The rest start in either the sublingual glands or the minor glands.

It is much more common to have a non cancerous (benign) lump in these glands, than cancer. Around 3 out of 4 tumours in the parotid gland (around 75%) are benign. Around half (around 50%) of the tumours found in the submandibular glands are benign.

Sublingual gland tumours are very rare, but are often cancer.

To learn more about salivary gland cancer visit: https://www.cancerresearchuk.o....rg/about-cancer/sali

Tumors of Salivary Glands Part 3- Adenoid cystic carcinoma
Reference- Shafer's textbook of oral pathology,Oral and maxillofacial pathology Brad.Neville
Time tags:
Introduction : 0:25
Clinical features- 2:25
Perineural invasion - 5:15
Histopathology - 6:17
Treatment- 11:10
Summary- 12:00

Christy, a survivor living with head and neck cancer, shares her cancer story. For more information on head and neck cancer, visit https://www.cancersupportcommu....nity.org/head-neck-c

This video is based on salivary gland tumor "ADENOID CYSTIC CARCINOMA ". It is explained in a easy and brief manner as simple as possible for you guys. The video also contains well illustrated diagrams, and clinical pictures to get a better overview of the pathology.

#adenoidcysticcarcinoma, #salivaryglanddisorders, #salivaryglandtumors, #cylindroma, #oralpathology, #dentistry, #histologyadenoidcysticcarcinoma