What is colorectal carcinoma? Colorectal carcinoma, also known as colon cancer, is when malignant or cancerous cells arise in the large intestines, which includes the colon and rectum.

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Video was part of 2014 Summer Scholarship Project with CSIRO called "The Hungry Microbiome"
For more visit: http://www.csiro.au/hungrymicrobiome/

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A Wesley Chapel man is calling on the community to take their health screenings seriously after what he thought was a cold, turned out to be cancer. ABC Action News reporter Rochelle Alleyne shares his story. https://www.abcactionnews.com/....news/region-hillsbor

Colorectal cancer is the third-most commonly diagnosed cancer in the U.S. and the second-leading cause of cancer-related deaths in both men and women. Learn more about colorectal cancer diagnosis and treatment at Mayo Clinic: https://mayocl.in/3ci7fyA

Colorectal cancer is one of the most preventable cancers, yet one in three persons who are eligible don't undergo the recommended screening tests. Colon and rectal cancer are thought of as a disease of the elderly, however, the last 20 to 30 years, there's been a shift into patients that are younger than 50 years old. Given this change in trend, the American Cancer Society has recommended a decrease age of average risk screening to 45 years.

Reporting from ASCO 2023 Annual Meeting, Sebastian Stintzing discusses refined approaches in patient's selection for neoadjuvant chemotherapy alone with selective use of chemoradiation in locally advanced CRC (PROSPECT and NeoCol studies). Regarding precision medicine approaches, he highlights the potential of liquid biopsy in detecting and monitoring RAS wt mCRC (FIRE-4 study) and confirms targeting opportunities for heavily pre-treated patients with HER2-positive, late-stage mCRC (DESTINY-CRC2 study).

Abstracts discussed:
- LBA2: PROSPECT: A randomized phase III trial of neoadjuvant chemoradiation versus neoadjuvant FOLFOX chemotherapy with selective use of chemoradiation, followed by total mesorectal excision (TME) for treatment of locally advanced rectal cancer (LARC) (Alliance N1048).
- Abstract 3503: Phase III randomized clinical trial comparing the efficacy of neoadjuvant chemotherapy and standard treatment in patients with locally advanced colon cancer: The NeoCol trial.
- Abstract 3507: Phase III FIRE-4 study (AIO KRK-0114): Influence of baseline liquid biopsy results in first-line treatment efficacy of FOLFIRI/cetuximab in patients with tissue RAS-WT mCRC.
- Abstract 3501: Trastuzumab deruxtecan (T-DXd) in patients (pts) with HER2-overexpressing/amplified (HER2+) metastatic colorectal cancer (mCRC): Primary results from the multicenter, randomized, phase 2 DESTINY-CRC02 study.

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During the colorectal cancer diagnosis process, the care team will perform tests to determine the cancer stage and whether it has spread. Watch as an oncologist describes the process, and learn more at https://www.cancercenter.com/c....ancer-types/colorect

Chapters
00:00 - Tests to Diagnose Colorectal Cancer
0:35 - Staging Colorectal Cancer
1:10 - PET Scans for Colorectal Cancer
2:31 - Treating Metastatic Colorectal Cancer

Tonia Young-Fadok, M.D., a colorectal surgeon at Mayo Clinic in Arizona, reviews the anatomy of the large intestine and discusses the staging of colorectal cancer. To learn more about colorectal cancer care at Mayo Clinic, visit: https://mayocl.in/2sDvtQv

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