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Wobbly Gait in Germ Cell Tumor Encephalitis
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• 06/29/23
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Patients with germ cell tumors may develop paraneoplastic encephalitis, and immunoglobulin G autoantibodies to Kelch-like protein 11 (KLHL11) have been identified as a biomarker. This video demonstrates ataxia in a patient with autoimmune KLHL11 encephalitis, which may also include diplopia, nystagmus, dysarthria, hearing loss, tinnitus, and vertigo. Click https://youtu.be/GPqg1sk4Jv0 for demonstration of nystagmus, https://youtu.be/2Pw2mc02iDg for illustration of dysarthria in the same patient, and https://ja.ma/3hx6aUH for full clinical details from a case series of patients with testicular cancer-related KLHL11 encephalitis.
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