What Is the Role Chemotherapy in Modern Day Prostate Cancer Treatment? | Evan Yu, MD Explains | PCRI

Watch DAY 1 of our 2020 virtual conference here: https://youtu.be/vThfzQCTKCc (featuring Daniel Margolis, MD on prostate imaging and Laurence Klotz, MD on active surveillance)

Watch DAY 2 here: https://youtu.be/RFwFbpSbj0Y (featuring Nicholas J. Vogelzang, MD, FASCO, FACP on treatments for advanced prostate cancer and Mack Roach, MD on radiation treatments)

Public health expert and PCRI moderator, Mark Moyad, MD, MPH, asks medical oncologist, Evan Yu, MD, about the role of cytotoxic chemotherapy in the optimal treatment of prostate cancer as of 2020 and into the near future.

0:09 Dr. Moyad asks Dr. Yu why chemotherapy is still so prevalent in the treatment of prostate cancer despite being perceived as archaic, and he asks Dr. Yu to describe the scenarios in which he would consider chemotherapy for a patient.

1:10 Dr. Yu defines chemotherapy and specifies that oncologists use the word to describe cytotoxic chemotherapies that poison rapidly dividing cells.

2:15 Dr. Yu posits that cytotoxic chemotherapies are unpopular because they are non-specific and attack all rapidly dividing cells. There is a desire to get more specific, perhaps genetically targets medicines.

2:35 Dr. Yu argues that cytotoxic chemotherapies still have an important role in prostate cancer.

3:22 Dr. Moyad asks Dr. Yu about sequencing (the order in which medicines are used) Taxotere and Jevtana, the two cytotoxic chemotherapies approved for prostate cancer. He also asks about other chemotherapies not yet approved for the treatment of prostate cancer, but still sometimtes used (e.g. Carboplatin).

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  Prostate Cancer