The future of ADCs in gastric and colorectal cancers
Kristen Ciombor, MD, MSCI, Vanderbilt-Ingram Cancer Center, Nashville, TN, discusses the potential role antibody-drug conjugates (ADCs) will play in the management of gastrointestinal cancers. The Phase II TROPION-PanTumor03 trial (NCT05489211) of datopotamab deruxtecan, a TROP2-directed ADC, has demonstrated the potential of ADCs in a variety of solid tumors including lung and breast cancers. Other ADCs such as trastuzumab deruxtecan have also shown promising benefits in gastric and colorectal cancers. This interview took place at the ESMO World Congress on Gastrointestinal Cancer (WCGIC) 2023 in Barcelona, Spain.
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