The Amyloidosis Forum | November 18, 2022 | Morning Sessions

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11/23/23

Recording of the Morning Sessions from the Amyloidosis Forum: Potential Pathways for Development of Imaging Endpoints for Clinical Trials in AL and ATTR Amyloidosis, hosted at the U.S. Food and Drug Administration's White Oak Campus in Silver Spring, Maryland on November 18, 2022.

The Morning Sessions were moderated by the meeting chair, Sharmila Dorbala MD, MPH, MASNC, Director of Nuclear Cardiology at Brigham and Womenโ€™s Hospital.

Each session can be viewed at the following timestamps:

0:00 - Welcome and Introductions (Isabelle Lousada & Rosalyn Adigun)
9:39 - Overview: The Central Role of Imaging-Based Biomarkers (Sharmila Dorbala)
21:55 - Animal Models for AL and ATTR Amyloidosis and the Need for Imaging (Christophe Sirac & Kevin Alexander)
30:23 - (Imaging) Biomarkers in Drug Development (Preston Dunnmon)
41:33 - Echocardiography: AL and ATTR Amyloidosis (Rodney Falk, Ashutosh Wechalekar, Grace Lin, Sarah Cuddy, & Cristina Quarta)
50:25 - Moderated Discussion: Echocardiography
1:12:02 - Cardiac MRI: AL and ATTR Amyloidosis (Marianna Fontana, Frederick L. Ruberg, Justin L. Grodin, Michael Jerosch-Herold, & Michela Brambatti)
1:21:56 - Moderated Discussion: Cardiac MRI
1:47:03 - Honoring Claudio Rapezzi (Mathew S. Maurer)
1:48:38 - Molecular Imaging of Amyloidosis-SPECT: ATTR Amyloidosis (Sharmila Dorbala, Mathew S. Maurer, Brett W. Sperry, Omar Abou Ezzeddine, Prem Soman, & John Vest)
1:59:44 - Moderated Discussion: Molecular-SPECT
2:18:47 - Molecular Imaging of Amyloidosis-PET: AL and ATTR Amyloidosis (Sharmila Dorbala, Michele Emdin, Jens Sรถrenson, Jonathan S. Wall, Spencer Guthrie, & Andrew Stephens)
2:30:59 - Moderated Discussion: Molecular-PET
2:48:49 - Connecting Changes in Amyloid Through Imaging with Changes in Cardiac Events, Functional Measures, & Health-Related Quality of Life (Ashutosh Wechalekar & Brett W. Sperry, moderated by Sarah Cuddy)
3:13:32 (Moderated Discussion: Standardization of Imaging in AL/ATTR Research)


Meeting recorded live via Zoom

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