Putting Spotlight on Systemic Mastocytosis: Multidisciplinary Look at Early Diagnosis and Management
View this program in its entirety here: https://www.exchangecme.com/spotlightonsm
Presented by: Mariana C. Castells, MD; Tracy I. George, MD; Matthew J. Hamilton MD; Karin Hartmann, MD
Description:
Systemic mastocytosis (SM) is a group of rare disorders characterized by accumulation of mast cells in internal tissues and organs, such as the liver, spleen, bone marrow, and small intestines. Patients with SM experience symptoms that include anaphylaxis, flushing, gastrointestinal issues, fatigue, and skin lesions; the lack of specific symptoms often makes diagnosis challenging, and clinicians should be aware of the array of symptoms and signs that indicate SM. More than 90% of patients with SM have a KIT D816V mutation, which, along with serum tryptase and bone marrow biopsy, is key to diagnosing SM. Management strategies for nonadvanced SM are largely symptomatic treatment, though there are targeted therapies in clinical trials. During this Clinical Research Updates™ webcast, a multidisciplinary expert panel will review the evidence and best-practice recommendations for the early diagnosis and treatment of SM, including keys to differential diagnosis, recommendations for management, and results and progress from new clinical trials. Included within this educational activity is an “Ask the Experts” chat box feature, allowing learners to submit questions that will be answered by program faculty.
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