Overcoming resistance to CAR-T therapy in CLL with ibrutinib & venetoclax

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07/14/23

Marco Ruella, MD, University of Pennsylvania, Philadelphia, PA, discusses strategies to overcome resistance to CAR-T therapy in chronic lymphocytic leukemia (CLL), commenting on the addition of ibrutinib and venetoclax to CAR-T therapy, and highlighting the use of gene editing techniques to engineer improved CAR-T constructs. This interview took place at the 2022 European Research Initiative on CLL (ERIC) Meeting.

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