Medical Genetics of Chronic Lymphocytic Leukemia

https://www.amazon.com/Medical....-Genetics-Chronic-Ly This article collection reviews the medical genetics of chronic lymphocytic leukemia and includes 20 papers by various authors. Topics include: Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics; Role of microRNA in chronic lymphocytic leukemia onset and progression; Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia; Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlations; The genomic landscape of chronic lymphocytic leukemia: clinical implications; Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance; Clinical significance of microRNAs in chronic and acute human leukemia; TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing; Chronic lymphocytic leukemia with clinical debut as neurological involvement: a rare phenomenon and the need for better predictive markers; NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients; Genetic methylation and lymphoid malignancies: biomarkers of tumor progression and targeted therapy; Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia; Global DNA methylation profiling reveals new insights into epigenetically deregulated protein coding and long noncoding RNAs in CLL; Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens; A Japanese case of chronic lymphocytic leukemia with t (1;6); Leptomeningeal involvement in B-cell chronic lymphocytic leukemia: a case report and review of the literature; Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies; Characterizing and prognosticating chronic lymphocytic leukemia in the elderly: prospective evaluation on 455 patients treated in the United States; Using gene co-expression network analysis to predict biomarkers for chronic lymphocytic leukemia; and Monoallelic and biallelic deletions of 13q14 in a group of CLL/SLL patients investigated by CGH Haematological Cancer and SNP array (8x60K).

• Category

  Leukemia - Chronic Lymphocytic - CLL