Live Class on Retinoblastoma-Treatment by Dr Suguna

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07/16/23

RetinoblastomaTreatment
FOCAL SYSTEMIC ENUCLEATION
RB-Treatment
Cryotherapy
Intravenous
Laser photocoagulation
Trans pupillary
Thermotherapy
Chemotherapy
Intravitreal Intra arterial
Success rates 95%
[VEC] – 6 cycles
S/E – deafness
DOC- MELPHALAN Into Ophthalmic A.
• MELPHALAN
• TOPOTECTAN
• CARBOPLATIN
FOCAL ENUCLEATION SYSTEMIC
RB-Treatment
Retinoblastoma –Treatment
• Advanced intra ocular RB with NVI (Neovascularization of Iris)
• Secondary Glaucoma
• AC invasion
• 75 % of vitreous volume involvement
• Hyphema
• Necrotic tumors with orbital inflammation
RB –Cause Of Death
1. Metastasis
• Occurs within 1 year
• M/C mode of metastasis → via Optic Nerve → CNS
2. Intra cranial Malignancy
• Pinealoblastoma
• TRILATERAL RB → B/L Retinoblastoma + Pinealoblastoma
3. Secondary Tumors
• Osteosarcoma of femur (m/c secondary tumor)
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