July 2020 Gyn Pathology Journal Club - Germ Cell Tumors of the Ovary

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06/29/23

Presentations on recent articles by Pathology Trainees. Special thanks to this month's presenters, Dr. Sameera Rashid, Dr. Veronica Ullici, and Dr. Fouad Zakka.

Link to this month's follow-up quiz and evaluation: https://www.notion.so/July-Ova....ry-Germ-cell-tumors-

This month's articles were:
- Hubbard AK, Poynter JN. Global incidence comparisons and trends in ovarian germ cell tumors by geographic region in girls, adolescents and young women: 1988-2012. *Gynecol Oncol*. 2019;154(3):608-615. doi:10.1016/j.ygyno.2019.06.025
- Heskett MB, Sanborn JZ, Boniface C, et al. Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components. *Mod Pathol*. 2020;33(6):1193-1206. doi:10.1038/s41379-019-0446-y
- Snir OL, DeJoseph M, Wong S, Buza N, Hui P. Frequent homozygosity in both mature and immature ovarian teratomas: a shared genetic basis of tumorigenesis. *Mod Pathol*. 2017;30(10):1467-1475. doi:10.1038/modpathol.2017.66

Disclaimer: This video does not constitute medical advice. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions.

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