Diffuse Large B-Cell Lymphoma Diagnosis& Treatment | Aggressive B-Cell Non-Hodgkin’s Lymphoma

►👨‍🏫💊Antibiotics Lectures: https://www.medicosisperfectio....nalis.com/products/c ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectio....nalis.com/products/c and use the PROMO code: ELECTROLYTES50 to get a 50% discount. ► Get my hand-written hematology video notes and my Prefectionalis Ultimate Notebook (PUN) at https://www.patreon.com/medicosis/ ...

Hematological malignancies can be divided into leukemias, lymphomas, and multiple myeloma.

Lymphomas can be divided into Hodgkin's lymphoma and non-Hodgkin's lymphoma.

Non-Hodgkin's lymphoma can be subdivided into aggressive lymphoma and indolent lymphoma.

Aggressive non-Hodgkin's lymphomas include:
*Diffuse large B-cell lymphoma​ (DLBCL)
*Burkitt's lymphoma.
*Mantle cell lymphoma.
*Precursor T-cell lymphoblastic lymphoma.
*B-lymphoblastic lymphoma.


Indolent non-Hodgkin's lymphomas include:
*Follicular lymphoma
*Marginal zone B-cell lymphoma (MALToma)
*Hairy cell leukemia/ lymphoma.
*Waldenstrom macroglobulinemia.
*Mycosis fungoides/ Sezary syndrome.

Diffuse Large B-cell lymphoma (DLBCL) is an aggressive Non-Hodgkin's lymphoma (NHL)...It's the most common NHL.

To diagnose, you need a core needle biopsy or an excisional biopsy of the lymph node

Uric acid levels can be high---Give allopurinol (Xanthine oxidase inhibitor).

Staging of cancer is important (Ann-Arbor classification based on history, physical exam and CT scan)

Treatment: Combination Chemotherapy (R-CHOP) regimen.

Tumor lysis syndrome can ensue.

PET scan is helpful.


The lymph node is a bean-shaped body (not a gland) that interrupts the flow of lymph through the lymphatic vessels.

Afferent lymphatics go towards the lymph node, while efferent exits the node. The lymph node has cortex (which contains the follicle, germinal center, mantle, and margin).

Lymphocyte activation and differentiation occur in the lymph node.

Lymph is a colorless fluid that floats in the lymphatic vessels (lymphatics) of your lymphatic systems.

Formed from the interstitial fluid (extracellular fluid) and returns back to the big veins (Superior vena cava) through the thoracic duct and Right lymphatic duct.

Lymph slows down when it passes in lymph nodes.

Lacteals are a special type of lymph, they are milky because they contain chylomicrons.

Lymph node enlargement can happen in cases of lymphoma (painless lymphadenopathy) or infection (painful).


Thanks for watching…
Don't forget to subscribe...and ring the bell to get notified.



► PLEASE SUPPORT MY CHANNEL ON “PATREON” TO GET EARLY ACCESS TO MY VIDEOS, PLUS OTHER MATERIALS AND NOTES https://www.patreon.com/medicosis

Don’t forget to check my recommended collection of the best medical books that I personally use https://www.amazon.com/shop/me....dicosisperfectionali



MEDICAL Sources that I use for my videos:-

► Goljan Rapid Review Pathology, https://amzn.to/2MufTPw
► Harrison’s Internal Medicine https://amzn.to/2OJiVNf
► Goldman-Cecil Medicine https://amzn.to/2N0v93u
► Davidson’s Principles and Practice of Medicine https://amzn.to/2vTmf1p

-------------------------------------------------------------------------


Many people ask me “How do you record your videos”?
Here is the answer:-

Equipment that I use:-

► Apple iPad Pro https://amzn.to/2nKCyZW
► Apple pencil https://amzn.to/2PimMCc
►Iphone holder kit: https://amzn.to/2OVV3aj
►Rode Video Mic Go: https://amzn.to/2OVF4Je
►Rode SC7 3.5mm TRS to TRRS Patch Cable: https://amzn.to/2vu2WeY
►Extension Audio Cable https://amzn.to/2nIDApo
►Rode DDC-GO DeadCat Artificial Fur Wind Shield for VideoMic GO: https://amzn.to/2OpbV8m




Disclaimer 1: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.
I am NOT a licensed physician…Talk to your doctor.

Disclaimer 2: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.



Got a question? Ask it in the comments section below, or connect with me on FACEBOOK https://www.facebook.com/medicosis/ where you can directly message me…I respond to your messages personally. Thanks!

Whether you’re studying for the USMLE, MCAT, shelf exam, NCLEX, COMLEX, PLEB, MCCEE, AMC_CAT, PANCE,…etc., these videos will help! Take it to the bank :)

As always…Be safe, Stay happy and Study hard!

MEDICOSIS PERFECTIONALIS If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
► Visit my website: https://www.medicosisperfectionalis.com/ My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/ 📱Save on your mobile phone bill: http://fbuy.me/q6bMj 🏦 Qbank (TrueLearn): https://truelearn.referralrock.com/l/MEDICOSIS/

• Category

  Lymphoma - Non-Hodgkin