Androgen Deprivation Therapy ADT in Prostate Cancer Treatment with Rana Mckay, MD EP 63

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07/13/23

#prostatehealth #prostatecancer #testosterone #testosteronereplacementtherapy #AndrogenDeprivationTherapy

Join Dr. Geo in this episode as he engages in a fascinating conversation with Dr. Rana McKay, a renowned medical oncologist specializing in prostate, bladder, kidney, and testicular cancer. As an associate professor at UC San Diego School of Medicine, Dr. McKay delivers exceptional patient care and imparts her extensive knowledge to medical students, residents, and fellows.
They uncover valuable insights into the average duration of ADT's effectiveness for men confronting advanced prostate cancer.

This approach offers significant promise by utilizing medications to lower androgen levels and impedes the growth of prostate cancer cells. Furthermore, Dr. Geo and Dr. McKay delve into the fascinating realm of bipolar androgen therapy, an alternative approach that involves carefully calibrated testosterone doses. This discussion challenges conventional wisdom and expands our understanding of the potential benefits of this therapeutic strategy.
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Chapters๐Ÿ“š
00:00 Androgen Deprivation Therapy [ADT] in Prostate Cancer Treatment with Rana Mckay, MD
09:28 It's not all about survival
11:06 How do you define advanced prostate cancer?
15:49 Do you categorize somebody that's a metastatic disease imaging
17:35 How can we chemically castrate these men?
20:38 Hormone therapy is one of the very first targeted therapies
22:15 Three methods of reducing testosterone
23:15 These hormones then go to two places
24:39 Gleason nine
28:32 There are two FDA-approved, anti-androgen called Begar Relics
33:52 Abiraterone for a period of time for localized disease
42:40 It impacts my ability to get them targeted therapies.
45:14 Why are we doing the PSA?
48:15 What is your approach for intermittent engine therapy?
50:03 A PSA velocity
50:52 A landmark study called Embark
52:11 The combination of Lupron plus Enzalutamide
55:58 The quality of life is good except for sexuality
01:02 Powerful hormone, testosterone
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DISCLAIMER: This video is educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Geovanni Espinosa, N.D., will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video, including but not limited to economic loss, injury, illness, or death.

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