Amyloidosis

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11/23/23

In medicine, amyloidosis is a non-specific term that refers to a number of different diseases collectively called amyloidoses. Amyloids are proteins whose secondary structure changes, causing the proteins to fold in a characteristic form, the beta-pleated sheet. When the normally soluble proteins fold to become amyloids, they become insoluble and deposit in organs or tissues, disrupting normal function. Different types of amyloidoses have different signs and symptoms depending on where and in which organs the amyloid proteins aggregate. Amyloidoses can be inherited or acquired.

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