Targeting ESR1 mutations early with camizestrant and a CDK4/6 inhibitor may help delay bone disease and improve quality of life, according to Dr. Massimo Cristofanilli during an interview with CURE at the 2025 ASCO Annual Meeting. #breastcancer #oncology

Cristofanilli explains that controlling bone involvement, which often causes pain and reduced quality of life, is a major goal. Early targeting of ESR1 may not only delay progression but also potentially extend survival by halting the mutation’s impact before further damage occurs.

Cristofanilli is the director of Breast Medical Oncology, professor of Medicine, and associate director of Precision Oncology at Weill Cornell Medicine; attending physician at New York-Presbyterian.

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CURE has become the largest consumer magazine in the United States, focusing entirely on cancer. With a total circulation of 285,000, individual subscribers account for over 140,000 of that figure, with the remainder including cancer centers and advocacy groups around the country. CURE’s time-tested approach combines science, humanity and technology to make cancer understandable for patients and their caregivers.

What do positive lymph nodes mean for breast cancer? Why do lymph nodes matter in breast cancer? How do lymph nodes influence treatment options and prognosis? Is there a difference between lymph node metastasis and metastatic breast cancer? In this video, Dr. Jennifer Griggs explains everything you need to know about lymph node involvement in breast cancer.

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Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.

What does your breast cancer stage mean? How do doctors determine the stage of breast cancer? How are different breast cancer stages treated? In this video, Dr. Jennifer Griggs explains everything you need to know about the staging system for breast cancer.

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Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.

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Will I survive my breast cancer? Will my cancer come back? In this video, Dr. Jennifer Griggs explains everything you need to know about breast cancer prognosis based on the tumor stage and biology.

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• Predict (Breast Cancer Survival Rate Calculator developed by the NHS) – https://breast.predict.nhs.uk/tool

#breastcancersurvivor #cancersurvival #breastcancerdiagnosis
Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.

With stage IV, the breast cancer has spread to other parts of your body. Often the bones, brain, lungs, or liver are affected. Because multiple areas may be involved, focused treatments like surgery or radiation alone may not be enough. Treatment of stage IV doesn’t cure the disease. But by shrinking the cancer, it can often slow it down, help you feel better, and let you live longer. Patients with stage IV breast cancer may live for years, but it’s usually life-threatening at some point.
As with primary breast cancer, treatment for stage 4 breast cancer, such as chemotherapy or radiation, can often be harsh and unforgiving. But dealing with an incurable illness and the side effects of its treatment aren’t the only burden MBC patients have to bear. Many also have to educate others about their disease, explaining over and over that no, the scans and blood tests and treatments will never come to end. No, the metastasized breast cancer in their lungs is neither lung cancer nor linked to smoking. No, staying positive and “just fighting hard” isn’t going to beat back their late-stage disease.
Stage 4 breast cancer can go into remission, meaning that it isn’t detected in imaging or other tests. Pathological complete remission (pCR) indicates a lack of cancer cells in tissues removed after surgery or biopsy.
But it’s rare to take tissue samples while treating stage 4 breast cancer. This could mean that although treatment has been effective, it hasn’t completely destroyed the cancer.
Advances in stage 4 breast cancer treatments are helping to increase the length of remission.

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Recently diagnosed with breast cancer? In this video, Dr. Jennifer Griggs outlines 7 essential questions to ask your doctor. These questions are designed to help you fully understand your breast cancer diagnosis, explore treatment options, and prepare for your journey ahead.

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Chapters
0:00 Introduction
0:40 Question 1
1:41 Question 2
2:36 Question 3
3:34 Question 4
4:34 Question 5
6:15 Question 6
7:16 Question 7

#breastcancerdiagnosis #breastcancerfighter #breastcancertreatment

Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.