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Cardiac Amyloidosis: Navigating Diagnostic Challenges and Therapeutic Horizons in 2025
Cardiac Amyloidosis: Navigating Diagnostic Challenges and Therapeutic Horizons in 2025 administrator 0 Views • 1 month ago

Cardiac amyloidosis is a condition affecting over 300,000 people globally with rogue proteins invading the heart. This condition has long been a diagnostic puzzle but hope is on the horizon!

In case you missed it, the FDA has approved BridgeBio’s (BBIO) Acoramidis, also known as Attruby, a transthyretin stabilizer revolutionizing care for ATTR-CM. And that’s not all!

Vutrisiran, a promising RNA interference therapy, is making waves by reducing TTR production and cardiac events for ATTR amyloidosis patients. These breakthroughs are saving lives—and driving innovation.

If you are an accredited investor who is passionate about saving lives while growing your investment portfolio, Evergrowth Biohealthcare Capital can be a good fit for you.

#Biotech #cardiacamyloidosis #cardiac #hearthealth #heartdisease #HealthcareInnovation #GeneTherapy #BiotechInvesting #MedicalBreakthroughs #HealthcareTech #Biohealthcare #MedicalResearch #InvestingInHealth #investing #investment #fund #hedgefund

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Disclaimer: As a medical doctor/market expert, I’m not a registered investment advisor. Despite that I strive to provide the most accurate information, I neither guarantee the accuracy nor timeliness. Past performance does NOT guarantee future results. I reserve the right to make any investment decision for myself and my affiliates pertaining to any security without notification except where it is required by law. I am also NOT responsible for the actions of my affiliates. The thesis that I presented may change anytime due to the changing nature of information itself. Investment in stocks and options can result in a loss of capital. The information presented should NOT be construed as a recommendation to buy or sell any form of security. My articles and videos are best utilized as educational and informational materials to assist investors in your own due diligence process. That said, you are expected to perform your own due diligence and take responsibility for your actions. You should also consult with your own financial advisor for specific guidance, as financial circumstances are individualized. That aside, what I shared with you is not professional medical advice. I simply share with you what I share with my own family to help get more out of your life.

Amyloidosis Pathogenesis | Introduction | Pathology V-Learning for Medical Students
Amyloidosis Pathogenesis | Introduction | Pathology V-Learning for Medical Students administrator 1 Views • 1 month ago

Medical topics are sometimes difficult to understand. Welcome to sqadia.com we are here to guide you through the sea. Today, our discussion will revolve around Amyloidosis.

▬ 📌 Amyloidosis
Amyloidosis can be referred to as a disease characterized by tissue damage due to extracellular protein deposits or amyloids that interfere with normal functioning.

👉 Morphology of Amyloidosis
Protein deposits or amyloids can have two stable shapes:
🟡 Native form
🟡 Beta sheets (which then clump together to form amyloid fibrils).

We will discuss all these reasons ahead so stick around.

▬ 📌 Pathogenesis of Amyloidosis
If we talk about Amyloidosis pathophysiology, Misfolded proteins are cleaved by proteases which sometimes cannot handle the protein burden and misfolded proteins pile up or in some cases, proteins opt such a morphology that is resistant to breakage.

▬ 📌 Types of Amyloidosis
Let’s hover over the types and their mechanisms. Types include:
🔵 AL or primary amyloidosis
🔵 AA or secondary amyloidosis
🔵 Systemic amyloidosis
🔵 Localized amyloidosis

Watch the video for more details.

▬ 📌 Signs and Symptoms of Amyloidosis
Let’s explore about the signs and symptoms which encompass:
⚫️ Kidney (Swelling in face, ankle, and legs)
⚫️ Intestine (Malabsorption and weight loss)
⚫️ Heart (Palpitations)
⚫️ Brain (Memory loss)

▬ 📌 Diagnosis of Amyloidosis
Let us have a glance over the diagnosis of Amyloidosis. Diagnostic tools are:
🟢 Congo Red Stain
🟢 Polarized Light
🟢 Biopsy

▬ 📌 Treatment of Amyloidosis
Treatment of Amyloidosis involves,
🔴 Chemotherapy
🔴 Cardiac Care
🔴 Organ Transplantation

So that was all about an overview of our video on Amyloidosis pathogenesis!

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When the Doctor Becomes an Amyloidosis Patient
When the Doctor Becomes an Amyloidosis Patient administrator 0 Views • 1 month ago

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What if you are a doctor and diagnosed with amyloidosis, and now you’re a patient? In this episode we’ll be talking with Dr. Charles Schulman, a general cardiologist. He was on the staff at Beth Israel Deaconess Medical Center for over 53 years, until he retired in early 2024. Back in 2020 he was diagnosed with Wild-Type Transthyretin Amyloidosis with cardiomyopathy – or ATTRwt-CM. It’s an interesting situation to be in, with lots of questions to understand how being a doctor impacts your experience as a patient and vice versa. For an overview of amyloidosis, please see episode 2 (for clinicians) or episode 3 (for patients).

Overview of Amyloidosis for Patients
Overview of Amyloidosis for Patients administrator 0 Views • 1 month ago

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This episode of All Things Amyloid is an adaptation of Amyloidosis Support Groups’ patient education video narrated by Michael York. You’ll hear a brief yet comprehensive overview of amyloidosis designed specifically for patients. It discusses what amyloidosis is, the wide range of symptoms, and which organs are typically involved. It focuses on the most common types, AL (light chain) and TTR (transthyretin), and summarizes the kinds of treatments that are currently available. The video can be found on AmyloidAware.com (http://amyloidaware.com/) .

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