Dr Mark Litzow talks to ecancer at the European School of Haematology (ESH) meeting: International Conference on Acute Lymphoblastic Leukaemia about the novel indications for the use of an allogeneic haematopoietic stem cell transplantation (HSCT) for the treatment of acute lymphoblastic leukaemia (ALL).

He states that the use of a paediatric, intensive chemotherapy regimen is associated with better outcomes in young adults.

Dr Litzow also mentions the observation that patients with a negative MRD experienced better remission along with a more favourable outcome.

With these indications, along with additional genetic markers, he describes that a transplant may not be required for these patients.

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ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

This consist of two parts the current video is about L1 L 2 L3 which classified under FAB where as the second one is WHO .Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain.
#Leukemia
#AcuteLeukemia
#ALL

Prof Jean Soulier talks to ecancer at the European School of Haematology (ESH) meeting: International Conference on Acute Lymphoblastic Leukaemia about the various signalling pathways and targets in T-cell acute lymphoblastic leukaemia (ALL).

He describes the implications of the chromosome 6q deletion in this disease along with the possible therapeutic opportunities for this translocation.

As the chair of this session, Prof Soulier also outlines the other signalling pathways that were mentioned in the session, which include NOTCH1, IL7R/PTEN and JAK/STAT.

Sign up to ecancer for free to receive tailored email alerts for more videos like this.
ecancer.org/account/register.php

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

This consist of two parts the current video is about L1 L 2 L3 which classified under FAB where as the second one is WHO .Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain.
#Leukemia
#AcuteLeukemia
#ALL