Juvenile Polyposis Syndrome


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Juvenile polyposis syndrome
Juvenile polyposis syndrome: An autosomal dominant disorder in which polyps develop throughout the gastrointestinal tract in the first decade or two of life. People with the disease are at increased risk for developing gastrointestinal cancers. Abbreviated JPS. There can also be diarrhea, GI bleeding, and protein-losing from the intestinal wall. JPS is clearly heterogeneous (more than one entity) as regards causation. Some cases of JPS appear sporadic with no family history of juvenile polyposis, while other cases are due to mutations in the MADH4 gene on chromosome 18 or the BMPR1A gene on chromosome 10. Also known as juvenile intestinal polyposis (JIP), juvenile polyposis coli (JPC).
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This video explains all the salient features of juvenile polyps including pathogenesis, morphology, clinical features, complications, and treatment aspects.
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https://www.youtube.com/playli....st?list=PL0-Q_iDcO3a
General Features:
Occurs in children less than 5 yrs of age
Hamartomatous polyps
Single(Sporadic) or multiple(polyposis syndrome)
MC site is the rectum.
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Join Dr. Joseph Palermo for a review of Juvenile Polyposis syndromes. This stay current short belongs to a collection of Pediatric Polyposis Syndrome videos, which can be found on the StayCurrent App.
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