Womb Cancer | What improves survival in women with womb cancer after surgery? | Cancer Research UK

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07/09/23

Doctors usually treat womb cancer with surgery. Some women have radiotherapy after surgery, especially if there is a high risk that the cancer will come back. In this trial, women had stage 1 womb cancer that was at a high risk of coming back (grade 3). Or they had stage 2 or stage 3 womb cancer.

Radiotherapy to the pelvis can help to stop cancer coming back in that area of the body. But it can’t stop cancer coming back elsewhere in the body.

Doctors think that chemotherapy during and after radiotherapy will help stop cancer coming back in another part of the body. But they don’t know this for certain. All chemotherapy drugs have side effects. So it’s important that patients don’t have treatments that don’t work. Having chemotherapy and radiotherapy together is called chemoradiotherapy.

The aims of this trial were to:
find out if it’s better to have chemoradiotherapy or radiotherapy on its own after surgery for womb
learn more about the side effects of these treatments and how they affect quality of life

The PORTEC-3 trial is trying to find out if radiotherapy and chemotherapy after surgery could improve survial in women with womb cancer. Dr Melanie Powell talks about the trial.

Read more at:
https://www.cancerresearchuk.o....rg/about-cancer/find

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