What is Chronic Myeloid Leukemia (CML)?
Chronic myeloid leukemia (CML) occurs when too many white blood cells are produced, and a genetic change occurs in a blood forming stem cell. CML is caused by the abnormal gene BCR-AL causing an irregular production of the white blood cells the body doesn’t need. Patients with CML often do not present with symptoms and the disease is diagnosed accidentally when a physician is doing another workup. Patients that do present with symptoms often experience easy bleeding, fatigue, fever, weight loss, pain below the ribs, pale skin, and excessive sweating during sleep. CML is often a slow-growing leukemia but may change and become more aggressive. Tyrosine kinase inhibitors, or TKIs such as imatinib are a currently effective treatment used to help eliminate CML cells in the body. The Weill Cornell Medicine Richard T. Silver Myeloproliferative Neoplasms Center is participating in research initiatives to determine new drugs or drug combinations may be used to provide better treatment options for CML patients.
Learn more: https://silvermpncenter.weill.....cornell.edu/patients
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