Understanding Ewing's Sarcoma : A Rare Type of Cancer Among Adults
Dr G Satish Reddy, Head of Ortho-oncology, Aster Prime Hospital, Hyderabad educated us on Ewings Sarcoma.
Ewing sarcoma is actually a very rare tumor. It is actually less seen in the African and Asian populations. Mostly seen in the Caucasian population. In the US, you will see, per annum, about 200 Ewing sarcomas being reported.
It’s rare, but it’s a very aggressive lesion. It also occurs very commonly in children only, between 10 and 20 years of age. And it causes a lot of soft tissue damage. Originally, we were actually treating this with radiation therapy but now we have improvements in our chemotherapy. Now, even here we do chemotherapy and then plan for limb-sparing surgery and continue chemotherapy. And the exact cause for Ewing sarcoma is not known.
We think it is pointing towards a genetic mutation that occurs in humans and this uncontrolled multiplication of the cells. Normally when a cell multiplies, after a certain limit, the body’s feedback mechanism stops these from multiplying or the older cells die. Here instead of the older cells dying, they live along with the new cells being added. This is the basic mechanism that leads to carcinomas and sarcomas, and that is what is happening here.
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