- Diet
- Cancer
- Colorectal Cancer
- Prostate Cancer
- Breast Cancer
- Adenoid Cystic Carcinoma
- Amyloidosis
- Anal Cancer
- Appendix Cancer
- Astrocytoma - Childhood
- Ataxia-Telangiectasia
- Beckwith-Wiedemann Syndrome
- Bile Duct Cancer (Cholangiocarcinoma)
- Birt-Hogg-Dubé Syndrome
- Bladder Cancer
- Bone Cancer (Sarcoma of Bone)
- Brain Stem Glioma - Childhood
- Brain Tumor
- Breast Cancer - Inflammatory
- Breast Cancer - Metastatic
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- Childhood Cancer
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- Lymphoma - Hodgkin - Childhood
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- Lymphoma - Non-Hodgkin
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- Multiple Myeloma
- MUTYH (or MYH)-Associated Polyposis
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- Nasal Cavity and Paranasal Sinus Cancer
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- Neuroblastoma - Childhood
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- Pleuropulmonary Blastoma - Childhood
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- Salivary Gland Cancer
- Sarcoma - Kaposi
- Sarcomas, Soft Tissue
- Skin Cancer (Non-Melanoma)
- Small Bowel Cancer
- Stomach Cancer
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- Thyroid Cancer
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- Unknown Primary
- Uterine Cancer
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- Werner Syndrome
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- Burkitt Lymphoma
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- Merkel Cell Carcinoma
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- Cancer in Young Adults
- Exercise and Cancer
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- Colostomy and Cancer
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- Music
Uncovering New, Synergistic Ways to Treat Tuberous Sclerosis Complex
Previous data has shown that early seizure control in children can improve learning as compared to those with poorer control. Some antiseizure medications are effective in individuals with TSC; although, there remains a portion of the population that remains refractory to the medications available. An ongoing phase 1/2 trial, TSC Steps (NCT04595513), is assessing whether treatment with TAV-18, a novel formulation of sirolimus, a mechanistic target of rapamycin (mTOR) inhibitor, can prevent or delay seizure onset in patients with TSC.
If successful, this study could have significant impacts on the way patients with TSC are treated, and the timing in which they receive treatment. Recently, NeurologyLive® sat down with trial investigator Darcy Krueger, MD, PhD, to discuss exploring different types of approaches to TSC, including combining therapies early in a patient’s diagnosis. Krueger, director of the Tuberous Sclerosis Clinic at Cincinnati Children’s, detailed the challenges with expanding ways to treat the disease, as well as provided commentary on the significance of TSC Steps and the thoughts of preventing seizures in TSC.
(https://www.neurologylive.com/....view/uncovering-new-
More Content on TSC Alliance:
- https://www.neurologylive.com/....sap-partner/tsc-alli
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