Targeted therapy effective for patients with advanced bladder cancer and specific gene mutations

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06/16/23

An international Phase II clinical trial led by researchers at MD Anderson Cancer Center found that treatment with the FGFR inhibitor erdafitinib resulted in a 40% response rate for patients with metastatic bladder cancers marked by mutations in the FGFR3 gene.

Arlene Siefker-Radtke, M.D., principal investigator on the trial and professor of Genitourinary Medical Oncology at MD Anderson, discusses the importance of this clinical trial for patients with bladder and other urothelial cancers.

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