Retinoblastoma | Ophthalmology Video Lecture | Medical Student V-Learning | sqadia.com

Retinoblastoma arises when tumour suppressor functions in the Retina are affected by the Mutations in the RB1 gene. This V-Learning™ lecture on Retinoblastoma elucidates the stages i.e. intraocular and extraocular stage of retinoblastoma along with their sub-stages. Details about classifications are also given. Likewise, treatment is elaborated including Cancer Chemotherapy, palliative therapy and enucleation.

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Lecture Duration: 00:45:32
Released: September 2019

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Tumours of the Retina are classified into primary tumours and secondary tumours. Moving on, retinoblastoma is elaborated which is a Cancer associated with Mutations in the retinoblastoma gene i.e. RB1 gene in the retina. Its heritable or germline cases and non-heritable or somatic cases are also discussed where the consequences related to RB1 gene are reported.

The intraocular stage of retinoblastoma delineates the two stages of growth pattern of retinoblastoma. One is the endophytic retinoblastoma which develops towards the vitreous cavity while the other is the exophytic retinoblastoma which is observed between the sensory Retina and retinal pigment Epithelium. Furthermore, Reese-Ellsworth classification comes under consideration along with ICRB classification.

Stage of extraocular extension is also highlighted. After explaining retinoblastoma diagnosis, the retinal Cancer Treatment is accomplished through chemotherapy, focal therapy, and palliative therapy. Likewise, surgical method is also elaborated over here which include enucleation and artificial prosthetic eye. At the end, light is shed on phacomatoses.
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• Category

  Retinoblastoma - Childhood