Nirogacestat improves outcomes for people with sarcoma, shows phase 3 clinical trial
#clinicaltrials #sarcoma
When Dana Avellino, now 36, first noticed a lump near her groin in the summer of 2018, she thought it was related her recent cesarean section. Her younger daughter was only 2 months old at the time. When a biopsy revealed that the lump was a sarcoma, a type of tumor that affects the body’s soft tissues, her doctors recommended that she go to Memorial Sloan Kettering Cancer Center (MSK).
After other treatments left her with severe side effects, Dana’s MSK doctor, sarcoma expert Mrinal Gounder, MD, told her about a clinical trial testing an experimental targeted drug called nirogacestat. Dana has now been taking the drug for more than three years. Her tumor, a rare, noncancerous subtype of sarcoma called a desmoid tumor, has shrunk so much that she can hardly feel it anymore.
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