MRI-Guided Transurethral Ultrasound Ablation (TULSA) in Patients with Localized Prostate Cancer
Laurence Klotz, MD, Professor of Surgery at the University of Toronto and Sunnybrook Chair of Prostate Cancer Research, discusses a newly FDA-approved treatment of localized prostate cancer: MRI-guided transurethral ultrasound ablation (TULSA). He explains how using MRI improves ablation technique, offers a technical overview of the procedure, and then reviews clinical trials of TULSA. As Dr. Klotz describes, MRI thermometry allows physicians to see what temperature the tissue is reaching during ablation, and the use of urethral and rectal cooling helps protect the urethra, making TULSA an effective treatment. He then explores a clinical study of MRI-guided TULSA conducted in five countries that showed a significant reduction of the prostate with minimal adverse effects.
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