Gestational trophoblastic disease
Gestational trophoblastic disease is a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception.
In gestational trophoblastic disease , a tumor develops inside the uterus from tissue that forms after conception (the joining of sperm and egg). This tissue is made of trophoblast cells and normally surrounds the fertilized egg in the uterus. Trophoblast cells help connect the fertilized egg to the wall of the uterus and form part of the placenta.
Sometimes there is a problem with the fertilized egg and trophoblast cells. Instead of a healthy fetus developing, a tumor forms. Until there are signs or symptoms of the tumor, the pregnancy will seem like a normal pregnancy.
Most GTD is benign and does not spread, but some types become malignant and spread to nearby tissues or distant parts of the body.
Gestational trophoblastic disease (GTD) is a general term that includes different types of disease:
1.Hydatidiform Moles
a)Complete HM.
b)Partial HM.
2.Gestational Trophoblastic Neoplasia (GTN)
3.Invasive moles.
4.Choriocarcinomas.
5.Placental-site trophoblastic tumors .
6.Epithelioid trophoblastic tumors.
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