Brain metastases developed from HER2 postive and triple negative breast cancer

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07/03/23

Dr Patricia Steeg speaks to ecancer at SABCS 2018 about the how brain metastases can develop from metastatic HER2 positive and triple negative breast cancer.

She reports that a mouse model has been used in order to find a drug that can prevent brain metastases from being developed from these subtypes, with the drug temozolomide showing significant capabilities of prevention.

Dr Steeg explains that a secondary metastases prevention trial has been set up with HER2 positive breast cancer patients who already have signs of brain metastases, with a primary endpoint of no additional brain metastases.

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