Bone Tumor. Reasons
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Most bone tumors start as one cell. This cell needs two different successful mutations in different parts of its DNA to become a tumor cell. First, it requires a mutation in the gene that regulates cell division. The second mutation needed is in the gene that destroys cells that are damaged.
When these gene mutations occur, the cells begin to multiply by dividing themselves. Since the damaged cells are not destroyed, tumor progression is rapid.
Depending on the how fast the cells divide, the tumor grows. In most cases, it takes nearly 10 years for a tumor to grow from a single cell to one billion cells, or to become one cubic centimeter in size.
A tumor of this size is detectable and can become symptomatic. That’s why, in most cases, malignant tumors have already metastasized at the time of diagnosis. They have had plenty of time to spread.
In case of secondary tumors, cancer cells that grow in different organs travel through the bloodstream to the bone, where they stay and begin to divide.
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