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07/05/23

June 21st, 2015

The 24th Annual Mark E. Nesbit Lectureship in Pediatric Oncology

“Li-Fraumeni Syndrome: Creating New Shields Against Damocles' Sword”

David Malkin, MD
Staff Oncologist,
Division of Hematology/Oncology,
Senior Scientist, Genetics & Genome Biology Program
The Hospital for Sick Children

Objectives:
1. Recognize the clinical phenotype of Li-Fraumeni syndrome and its variants.
2. Describe the molecular basis of phenotype diversity in Li-Fraumeni syndrome.
3. Appraise the opportunities and challenges of incorporating T53 genetic testing and clinical surveillance in potential TP53 mutation carriers.

*For more information about the University of Minnesota’s Pediatric Grand Rounds, click here: http://www.peds.umn.edu/education/grandrounds/
(CME credits are not granted for online viewing)

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