5 Genetic disorders that are strongly linked to pancreatic cancer | Dr. Praveen Kammar
1. BRCA Mutations:
BRCA Gene Mutations. Sometimes, changes or “mutations” occur that prevent genes from doing their job properly. Certain mutations in the BRCA genes make cells more likely to divide and change rapidly, which can lead to cancer.
2. FAMMM Syndrome:
Familial Atypical Multiple Mole Melanoma syndrome (FAMMM syndrome) is an autosomal dominant disorder characterized by the presence of multiple large moles of variable size and color with pigmentary leakage, associated with an increased incidence of malignant melanoma, pancreatic carcinoma
3. Peutz-jeghers syndrome:
Peutz-Jeghers syndrome (PJS) is characterized by the association of gastrointestinal (GI) polyposis and mucocutaneous pigmentation.
4. Lynch syndrome:
Peutz-Jeghers syndrome (PJS) is characterized by the association of gastrointestinal (GI) polyposis and mucocutaneous pigmentation.
5. Familial pancreatitis
Hereditary pancreatitis is a genetic condition characterized by recurrent episodes of inflammation of the pancreas.
Genetic testing is used by doctors to identify them.
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