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This is an update to Andrew's story from February, 2010. To see the Sharing Mayo Clinic - Part 1 story, visit: http://sharing.mayoclinic.org/....2010/02/08/it-really
The Sharing Mayo Clinic - Part 2 story can be found here: http://sharing.mayoclinic.org/....2011/08/23/pilocytic


8-year-old female with worsening headaches and emesis. There is a predominantly cystic, T1-hypointense, FLAIR mildlyhyperintense, and T2-hyperintense lesion centered within the pons and left brachium pontis. The lesion extends towards the left cerebellopontine angle and prepontine space where there is partial encasement and slight rightward displacement of the basilar artery. On the postcontrast images, there is a minimally enhancing mural nodule along its posteroinferior border. The imaging findings are consistent with a pilocytic astrocytoma. Pilocytic astrocytomas are well-circumscribed, slow-growing lesions, typically demonstrating a cyst with a mural nodule. The cerebellum is the most common site of involvement, followed by the optic nerve and chiasm, and then adjacent to the third ventricle. The differential diagnosis includes medulloblastoma, ependymoma, ganglioglioma and hemangioblastoma.
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Neuroradiology board review. This lecture is geared towards the ABR core exam for residents, but it would be useful for review for the ABR certifying exam or certificate of added qualification (CAQ) exam for neuroradiology.
This case shows
a teenager with T2 hyperintense mass in the left posterior fossa resulting in mass effect on the 4th ventricle. On post-contrast imaging there is scattered hazy enhancement throughout portions of the mass.
The diagnosis is:
pilocytic astrocytoma
Pilocytic astrocytomas are the most common brain tumors in children. They most commonly occur in the posterior fossa and are often characterized by a cystic mass with a nodular enhancing area. They are relatively benign tumors with a good 10 year survival.
When you encounter a cyst with a nodule, there is a relatively short differential diagnosis which includes:
Pilocytic astrocytoma
Ganglioglioma
Hemangioblastoma (has blood vessels/flow voids)
Plemomorphic xanthoastrocytoma - PXA
Check out this video and additional content on http://www.learnneuroradiology.com


28-year-old male with new onset seizure activity on the right. There is an infiltrating nonenhancing mass centered within the left superior frontal gyral subcortical white matter with infiltration of the overlong cortical grey matter. The lesion is T2/FLAIR hyperintense, T1 hypointense, and does not restrict on the diffusion weighed images. There is swelling of the left superior frontal gyrus with effacement of the surrounding cortical sulci. This is a case of a biopsy proven infiltrating grade 2 astrocytoma. Seizure is the most common presenting feature of low-grade gliomas. 2/3rds of cases involve the supratentorial white matter, with the frontal lobes affected in 1/3 of cases.
For more, visit our website at http://ctisus.com