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This is an abstract of clinical research conducted at the NIH Clinical Center and published in the Journal of Surgical Oncology, May 2019. A new program at the NIH Clinical Center for patients with hereditary gastric cancer syndromes incorporates comprehensive high-quality medical care and clinical and basic science research in a highly integrated, multidisciplinary setting.
For information on the:
•HDGC Center of Excellence at the NIH Clinical Center: https://go.usa.gov/xmSzm
•Full text of the journal article: https://go.usa.gov/xmSzG
•Research abstract video or links presented, email: davislb@nih.gov
Music: Epidemic Sound
Jeremy Davis, M.D., Surgical Oncologist at the Center for Cancer Research in the National Cancer Institute discusses a phase II clinical trial for patients with Hereditary Diffuse Gastric Cancer Syndrome.
https://ccr.cancer.gov/surgica....l-oncology-program/j
https://ccr.cancer.gov/clinical-trials
Gastric cancer/stomach cancer is the fifth most common cancer worldwide and multi-disciplinary management is the key. Recently, the molecular classification of gastric cancer has been updated in literature and it is showing prognostic significance. The Lauren classification is also discussed in the video and the pros and cons are compared with the molecular classification.
Dr. Nilesh Lokeshwar explains the basics of gastric cancer, and its hereditary predisposition and then embarks on the journey of explaining the molecular classification.
All four types are explained in requisite detail to aid in the understanding of the students. Microsatellite instability, chromosomal instability, genomic stability and Epstein Barr virus type-molecular types are discussed and their
prognostic relevance addressed.
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