Progressive descending facial nerve paralysis in amyloidosis

Dr Miles Kiernan at the Department of Ophthalmology, North Middlesex University Hospital NHS Trust, presents his Clinical Picture on hereditary gelsolin amyloidosis, published in The Lancet on 17 June 2023.

Read the full Clinical Picture here: https://www.thelancet.com/jour....nals/lancet/article/

Amyloidoses are a group of diseases characterised by the deposition of insoluble proteins which aggregate into distinctive fibrillar forms. Familial amyloid polyneuropathies are autosomal dominant in their inheritance and are defined according to the precursor protein of amyloid—transthyretin, apolipoprotein A-1, or gelsolin.

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