Tracy George, MD, The University of Utah, Salt Lake City, UT, discusses the impact of avapritinib therapy for patients with indolent systemic mastocytosis on mast cell numbers and phenotype. Systemic mastocytosis is a rare disease, and in patients with advanced indolent disease, avapritinib, a selective tyrosine kinase inhibitor of activated KIT and PDGFRA, has demonstrated efficacy as evaluated in the PIONEER study (NCT03731260). Avapritinib resulted in a vast reduction in the number of mast cells in patients with indolent systemic mastocytosis and also altered the immunophenotype of aberrant cells. This interview took place at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021.

Ramesh K. Ramanathan, MD, medical director, Clinical Trials Program, Virginia G. Piper Cancer Center, discusses the potential of identifying actionable targets in appendiceal cancers.

Gallbladder cancer is not as commonly known but is a very aggressive form of cancer. Dr. Susan Sharpe, surgical oncologist at The Sarah Cannon Center at Johnston-Willis Hospital, explains what the symptoms you should be looking for may be.

Cats with certain medical conditions may require a feeding tube to help them recover while they have an inability or lack of desire to eat on their own. This video showcases how to use and maintain an esophageal feeding tube in a cat. Topics covered include how esophageal feeding tubes work, gathering materials prior to feeding, daily bandage and tube care, preparing the food, how to administer food through the tube, and complications that may arise with the feeding tube and how to deal with them. Also included are pro tips such as giving medication through the tubes, optimum food consistency, and when to call your veterinarian. Pets needing at home feeding tube management should be under the care of a veterinarian.

MVA has developed a series of instructional videos for pet owners whose pets are under the care of a veterinarian. These videos are intended to reinforce home care skills, and should not be viewed as comprehensive tutorials.

Video Transcription:
Metropolitan Veterinary Associates, thanks you for considering us, as a source of information for your pet care. In the following video you will be shown techniques, for at-home treatments of common pet issues. If at any point, you do not fell comfortable performing these techniques, you should consider contacting your veterinarian. Remember, while it is possible to do these techniques with one person, it is always easier to do them with two people present. - Hi there, I'm Lisa. - And I'm Kara. We're both nurses at Metropolitan Veterinary Associates. - Today, we will be showing you how to use and maintain a feline feeding feeding tube. Feeding tubes are placed in cats, that either have the inability or lack of desire to eat on their own. They may remain in place, for weeks to many months with good management. - The materials you will need are canned food as prescribed by your veterinarian. Lukewarm water, a syringe for water, a syringe for food, triple antibiotic ointment, moistened cotton swab and an E-tube wrap. - Before we get started, it is important to understand how the feeding tube works. An esophageal feeding tube, enters the esophagus through a small skin incision and sits just prior to the stomach sphincter. It is then suture to the skin and covered with an E-wrap. A tube syringe, adapter and cap are placed on the end of the tube. - It is important to remember that the tube should always be caped and not open to air. - Pets can eat despite the feeding tube. If your pet is interested in food, allow them to eat and notify your veterinarian. Some pets may need encouragement, such as petting or talking to them while offering food or giving a taste on their lips. It is very important to only offer and encourage a little bit. And then remove the food until the next offering. Please be aware that cats can develop a food aversion when food is constantly around. - Medications may also be given through feeding tubes. They must either come as liquids or tablets and powders that can be dissolved well and water. Be sure to follow your veterinarians instructions about giving medications through the tube. It is very important that you flush the tube with water, before and after each feeding or medication administration. - Another aspect of a feline feeding tube, is daily bandage and tube care. The tube site should be cleaned at least once daily to prevent infection. Use a moistened cotton tip swab or clean damp cloth, to gently remove any cross or food debris from the site. Be sure to pat it dry prior to replacing the rap. Triple antibiotic ointment may be placed at the tube site to help prevent an infection. - The wraps should be changed and washed every other day. Be sure you can fit two fingers comfortably under that rap, to ensure it is neither too tight nor too loose. Always keep the tube contained under an E-tube wrap and ensure that the feeding tube is well secured. - In preparation for the feeding, mix the prescribed amount of food and water and blend to the desired consistency. The diet should be blended into a smooth gruel. You may also lightly warm the food, but be sure to mix thoroughly after doing so. Test the food like you would with a baby bottle and make sure the gruel is not too hot prior to feeding. - Now we will show you the steps for feeding a cat through the feeding tube. First, you will need to attach an empty syringe to the tube syringe adapter and pull back on the plunger to check for negative pressure. Negative pressure is a force working against you as you pull the plunger of the syringe back. When you pull on the plunger. It should be sucked back into the previous position. Continue to evacuate any air or food until you achieve negative pressure. If you are unable to get negative pressure, please stop and contact your veterinarian. Once negative pressure is achieved, slowly administer the recommended amount of pre-feeding water. Stop, if coughing or gagging occurs as this could reflect movement in the tube positioning...

Dive into the depths of Bone Tumours study at Medica Oncology Academic Meet. Join us to witness our Department of Musculoskeletal Onco Surgery present groundbreaking medical advancements and treatment prospects.

#MedicaOncology #AcademicMeet #BoneTumour #CME #Oncology #OncologyTreatment #Cancer #CancerCare #CancerTreatment #CancerAwareness #CancerSupport #BeatCancer

Naveen Pemmaraju, MD, discusses the need to move beyond JAK inhibition when treating patients with myeloproliferative neoplasms.

Srdan Verstovsek, MD, PhD, and Daniel J. DeAngelo, MD, PhD, provide insight on diagnostic criteria, prognostic factors and their outcomes, and mutations of importance in myelofibrosis.